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219861-08-2

219861-08-2 structure
219861-08-2 structure
  • Name: Escitalopram oxalate
  • Chemical Name: Escitalopram oxalate
  • CAS Number: 219861-08-2
  • Molecular Formula: C22H23FN2O5
  • Molecular Weight: 414.427
  • Catalog: API Nervous system medication Antidepressant, manic
  • Create Date: 2018-04-05 08:00:00
  • Modify Date: 2026-07-01 10:59:37
  • Escitalopram is a selective serotonin reuptake inhibitor (SSRI) with Ki of 0.89 nM.Target: SSRIsEscitalopram, the S-enantiomer of citalopram, belongs to a class of antidepressant agents known as selective serotonin-reuptake inhibitors (SSRIs). Escitalopram may be used to treat major depressive disorder (MDD) and generalized anxiety disorder (GAD). Escitalopram has no significant affinity for adrenergic (alpha1, alpha2, beta), cholinergic, GABA, dopaminergic, histaminergic, serotonergic (5HT1A, 5HT1B, 5HT2), or benzodiazepine receptors; antagonism of such receptors has been hypothesized to be associated with various anticholinergic, sedative, and cardiovascular effects for other psychotropic drugs. The chronic administration of escitalopram is found to downregulate brain norepinephrine receptors, as has been observed with other drugs effective in the treatment of major depressive disorder. Escitalopram does not inhibit monoamine oxidase.

Name Escitalopram oxalate
Synonyms Oxalic acid escitalopram
Lexapro (TN)
MFCD06407826
Lu-26-054-0
Escitalopram oxalateQ: What is Escitalopram oxalate Q: What is the CAS Number of Escitalopram oxalate Q: What is the storage condition of Escitalopram oxalate Q: What e the applications of Escitalopram oxalate
(1S)-1-[3-(diméthylamino)propyl]-1-(4-fluorophényl)-1,3-dihydro-2-benzofurane-5-carbonitrile oxalate
(S)-Citalopram-d6 Oxalate
Escitalopram Oxalate(Secondy Standds traceble to
ESCIFALOPRAMOXALATE
EscitalopraM oxalate S-(+)-CITAPROLAM OXALATE
(1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile ethanedioate
D-citalopraM oxalate
S-(+)-CITAPROLAM OXALATE
Citalopram Impurity 2((S)-Isomer)
Escitalopram oxalate citalopram
Citalopram Impurity 2
Escitalopram oxalate API
ESCITALOPRAM OXALATE
(1S)-1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile oxalate
5-Isobenzofurancarbonitrile, 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-, (1S)-, ethanedioate (1:1)
(S)-Escitalopram Oxalate
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofuran-carbonitrile oxalate
Escitalopram oxalate //BP
(S)-CITALOPRAM
5-Isobenzofurancbonitrile, 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-, (1S)-, ethanedioate (1:1)
[2H4]-Citalopram oxalate
1S)-1-[3-(Dimethylamino-d6)propyl]-1-(4-fluorophenyl)-1,3-dihydro -5-isobenzofurancbonitrile
(S)-Citalopram oxalate in methanol
[2H4]-Escitalopram Oxalate
Escitalopram for system suitability
Escitalopram D3 oxalateQ: What is Escitalopram D3 oxalate Q: What is the CAS Number of Escitalopram D3 oxalate Q: What is the storage condition of Escitalopram D3 oxalate Q: What e the applications of Escitalopram D3 oxalate
(S)-1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile Oxalate
Escitalopram oxalate, >=
1S)-1-[3-(Dimethylamino-d6)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancbonitrile Oxalate
Dexcitalopram oxalate
EscitalopraM API
Escitalopram for system suitability CRS
Ethandisäure--(1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorphenyl)-1,3-dihydro-2-benzofuran-5-carbonitril(1:1)
Citalopram S-Isomer (Escitalopram)
Escitalopram Oxalatea
(1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-3H-2-benzofuran-5-carbonitrile
Escitalopram (oxalate)
Escitaloptam-d4 Oxalate
Escitalopram oxalate CRS
Oxalate escitalopram
Escitalopram Oxalate (C1)
Escitalopram Oxalate, 10 mM in DMSO
Lexapro
(1S)-1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancbonitrile Ethanedioate
escitalopram oxalic acid
Escitaloprám oxalate
[2H4]- (S)-Citalopram Oxalate
Citalopram Impurity 2((S)-Isomer)(Escitalopram)
S-(+)-(dimethyl-amino)propyl-1-(p-fluorophenyl)-5-phthalancbonitrileoxalate
(1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-3H-isobenzofuran-5-carbonitrile
Cipralex
Escitalopram oxalate in Methanol
Escitalopram oxalate salt
Escitalopram Oxalate (Citalopram oxalate)
(1S)-1-[3-(diMethylaMino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile
(S)-Citalopram Oxalate
(1S)-1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile ethanedioate (1:1)
Escitalopram oxalate (USAN)
(S)-Citalopram-d6
Escitalopram Oxalate
(S)-CitalopramOxalate>
S-(+)-1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancbonitrile oxalate
Escitalopram oxalate a selective serotonin reuptake inhibitor
escitalopraM oxalat
CitalopraM S-IsoMer
Description Escitalopram is a selective serotonin reuptake inhibitor (SSRI) with Ki of 0.89 nM.Target: SSRIsEscitalopram, the S-enantiomer of citalopram, belongs to a class of antidepressant agents known as selective serotonin-reuptake inhibitors (SSRIs). Escitalopram may be used to treat major depressive disorder (MDD) and generalized anxiety disorder (GAD). Escitalopram has no significant affinity for adrenergic (alpha1, alpha2, beta), cholinergic, GABA, dopaminergic, histaminergic, serotonergic (5HT1A, 5HT1B, 5HT2), or benzodiazepine receptors; antagonism of such receptors has been hypothesized to be associated with various anticholinergic, sedative, and cardiovascular effects for other psychotropic drugs. The chronic administration of escitalopram is found to downregulate brain norepinephrine receptors, as has been observed with other drugs effective in the treatment of major depressive disorder. Escitalopram does not inhibit monoamine oxidase.
Related Catalog
References

[1]. Zhang, P., et al., Structure-activity relationships for a novel series of citalopram (1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbon itrile) analogues at monoamine transporters. J Med Chem, 2010. 53(16): p. 6112-21.

[2]. Pastoor, D. and J. Gobburu, Clinical pharmacology review of escitalopram for the treatment of depression. Expert Opin Drug Metab Toxicol, 2014. 10(1): p. 121-8.

Boiling Point 428.3ºC at 760 mmHg
Melting Point 152-153ºC
Molecular Formula C22H23FN2O5
Molecular Weight 414.427
Flash Point 212.8ºC
Exact Mass 414.159088
PSA 110.86000
LogP 2.96858
Storage condition -20°C Freezer, Under Inert Atmosphere
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases 26-36
RIDADR NONH for all modes of transport
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