Top Suppliers:I want be here



66335-38-4

66335-38-4 structure
66335-38-4 structure
  • Name: 5'-Deoxy-5-fluorocytidine
  • Chemical Name: 5'-Deoxy-5-fluorocytidine
  • CAS Number: 66335-38-4
  • Molecular Formula: C9H12FN3O4
  • Molecular Weight: 245.21
  • Catalog: Biochemical Nucleoside drugs Deoxynucleotides and their analogues
  • Create Date: 2018-06-17 15:12:39
  • Modify Date: 2024-01-02 14:25:23
  • 5-Fluoro-5'-deoxycytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].

Name 5'-Deoxy-5-fluorocytidine
Synonyms 5'-deoxy-5-fluoro-Cytidine
5'-Deoxy-5-fluorocytidine
MFCD07369278
Cytidine, 5'-deoxy-5-fluoro-
4-Amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyltetrahydro-2-furanyl]-5-fluoro-2(1H)-pyrimidinone
5'-Deoxy-5-fluoro Cytidine
Capecitabine Impurity 1
Description 5-Fluoro-5'-deoxycytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].
Related Catalog
References

[1]. Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8.  

Density 1.8±0.1 g/cm3
Boiling Point 437.9±55.0 °C at 760 mmHg
Melting Point 196-198ºC
Molecular Formula C9H12FN3O4
Molecular Weight 245.21
Flash Point 218.6±31.5 °C
Exact Mass 245.081177
PSA 110.60000
LogP -0.94
Vapour Pressure 0.0±2.4 mmHg at 25°C
Index of Refraction 1.700
Storage condition Hygroscopic, -20°C Freezer, Under Inert Atmosphere
Hazard Codes Xn: Harmful;Xi: Irritant;
Risk Phrases R20/21/22
Safety Phrases 26-36-37/39
RIDADR NONH for all modes of transport
HS Code 2934999090

~92%

66335-38-4 structure

66335-38-4

Literature: ANGIOGENE PHARMACEUTICALS LIMITED; THE GRAY LABORATORY CANCER RESEARCH TRUST Patent: WO2006/32921 A1, 2006 ; Location in patent: Page/Page column 37-38 ;

~95%

66335-38-4 structure

66335-38-4

Literature: MacDonald, Peter Lindsay; Rossetto, Pierluigi; Gallina, Maurizio Patent: US2009/209754 A1, 2009 ; Location in patent: Page/Page column 9-10 ;

~86%

66335-38-4 structure

66335-38-4

Literature: Procopio, Antonio; Gaspari, Marco; Nardi, Monica; Oliverio, Manuela; Romeo, Roberto Tetrahedron Letters, 2008 , vol. 49, # 12 p. 1961 - 1964

~%

66335-38-4 structure

66335-38-4

Literature: Chinese Chemical Letters, , vol. 21, # 2 p. 163 - 166

~%

66335-38-4 structure

66335-38-4

Detail
Literature: Chemical and Pharmaceutical Bulletin, , vol. 40, # 9 p. 2568 - 2571
HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%