30652-11-0
30652-11-0 structure
- Name: Deferiprone
- Chemical Name: deferiprone
- CAS Number: 30652-11-0
- Molecular Formula: C7H9NO2
- Molecular Weight: 139.152
- Catalog: Pharmaceutical intermediate Heterocyclic compound Pyridine compound Hydroxypyridine
- Create Date: 2018-07-24 00:21:55
- Modify Date: 2026-07-02 08:42:39
-
Deferiprone is the only orally active iron-chelating drug to be used therapeutically in conditions of transfusional iron overload. Target：Deferiprone is an orphan drug designed and developed primarily by academic initiatives for the treatment of iron overload in thalassaemia. Deferiprone has been used in several other iron or other metal imbalance conditions and has prospects of wider clinical applications. Deferiprone has high affinity for iron and interacts with almost all the iron pools at the molecular, cellular, tissue and organ levels. Doses of 50-120 mg/kg/day appear to be effective in bringing patients to negative iron balance. Deferiprone increases urinary iron excretion, which mainly depends on the iron load of patients and the dose of the drug.
| Name | deferiprone |
|---|---|
| Synonyms |
1,2-dimethyl-3-hydroxy-4(1h)-pyridinon
deferiprone(DFP) 3-Hydroxy-1,2-dimethyl-4(1H)-pyridone> 3-hydroxy-1,2-dimethyl-4(1h)-pyridon Deferrone 3-Hydroxy-1,2-dimethyl-1,4-dihydropyridin-4-one TIMTEC-BB SBB006753 1,2-dimethyl-3-hydroxy-4(1H)-pyridinone 3-Hydroxy-1,2-dimethyl-4(1H)-pyridinone Kelfer DEFERIDONE 1,2-DIMETHYL-3-HYDROXYPYRID-4-ONE 3-hydroxy-1,2-dimethyl-pyrid-4-one DEFERIPRONE PHMACEUTICAL RAW MATERIALS Deferiprone, 10 mM in DMSO deferipnone 3-HYDROXY-1,2-DIMETHYL-4(1H)-PYRIDONE DEFERIPRON 1,2-Dimethyl-3-hydroxy-1,4-dihydropyridine-4-one 3-hydroxy-1,2-dimethyl-4-pyridone Deferiprone CRS Deferione 1,2-DIMETHYL-3-HYDROXY-4-PYRIDONE MFCD00134497 UNII-2BTY8KH53L 3-hydroxy-1,2-dimethylpyridin-4-one 3-HYDROXY-1,2-DIMETHYL-4(1H)-PYRIDONE, 9 Deferiprone ISO 9001：2015 REACH Ferriprox eferiprone 3-hydroxy-1,2-dimethyl-4-pyridinone cp20(chelatingagent) 1,2-dimethyl-3-hydroxy-4(1h)-pyridinone 1,2-DIMETHYL-3-HYDROXYPYRIDINE-4-ONE 4(1H)-Pyridinone,3-hydroxy-1,2-diMethyl 1,2-dimethyl-3-hydroxy-4-pyridinone 1,2-Dimethyl-3-hydroxy-4-pyridone 20(chelatingagent) Debrisoquine Hemisulfate-13C DeferiproneQ: What is Deferiprone Q: What is the CAS Number of Deferiprone Q: What is the storage condition of Deferiprone Q: What e the applications of Deferiprone 3-hydroxy-1,2-dimethylpyridin-4(1H)-one 3-Hydroxy-1,2-dimethyl-4(1H)-pyridone DMHP 3-HYDROXY-1,2-DIMETHYL-4(1H)PYRIDINONE 1,2-DiMethyl-3-hydroxy-4-pyridone, R CP20 DEFERIPRONE 1,2-DIMETHYL-3-HYDROXYPYRIDIN-4-ONE 3-Hydroxy-1,2-diMethylpyridin-4(1H)-one |
| Description | Deferiprone is the only orally active iron-chelating drug to be used therapeutically in conditions of transfusional iron overload. Target：Deferiprone is an orphan drug designed and developed primarily by academic initiatives for the treatment of iron overload in thalassaemia. Deferiprone has been used in several other iron or other metal imbalance conditions and has prospects of wider clinical applications. Deferiprone has high affinity for iron and interacts with almost all the iron pools at the molecular, cellular, tissue and organ levels. Doses of 50-120 mg/kg/day appear to be effective in bringing patients to negative iron balance. Deferiprone increases urinary iron excretion, which mainly depends on the iron load of patients and the dose of the drug. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 232.7±40.0 °C at 760 mmHg |
| Melting Point | 272-275 °C(lit.) |
| Molecular Formula | C7H9NO2 |
| Molecular Weight | 139.152 |
| Flash Point | 94.5±27.3 °C |
| Exact Mass | 139.063324 |
| PSA | 42.23000 |
| LogP | -0.22 |
| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
| Index of Refraction | 1.565 |
| Storage condition | -20°C Freezer |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
|
| Hazard Codes | Xn:Harmful; |
|---|---|
| Risk Phrases | R22;R36/37/38 |
| Safety Phrases | S26-S36 |
| WGK Germany | 3 |
| RTECS | UU7785940 |
| HS Code | 2933399090 |
| Precursor 9 | |
|---|---|
| DownStream 1 | |
| HS Code | 2933399090 |
|---|---|
| Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |