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28094-15-7

28094-15-7 structure

28094-15-7 structure

Name: Oxidopamine hydrochloride
Chemical Name: 6-Hydroxy Dopamine Hydrochloride
CAS Number: 28094-15-7
Molecular Formula: C₈H₁₂ClNO₃
Molecular Weight: 205.63900
Catalog: Signaling Pathways GPCR/G Protein Dopamine Receptor
Create Date: 2018-08-03 15:40:20
Modify Date: 2026-07-03 14:33:54
Oxidopamine hydrochloride is a neurotoxic synthetic organic compound, selectively destroys dopaminergic and noradrenergic neurons in the brain.

Name	6-Hydroxy Dopamine Hydrochloride
Synonyms	1,2,3-Benzenetriol, 4-(2-aminoethyl)-, hydrochloride 1,2,4-Benzenetriol, 5-(2-aminoethyl)-, hydrochloride 5-(2-Aminoethyl)benzene-1,2,4-triol hydrochloride 2-(2,4,5-TRIHYDROXYPHENYL)ETHYLAMINE HYDROCHLORIDE 6-OHDA 2,4,5-TRIHYDROXYPHENETHYLAMINEYDOCHLORIDE 6-OHDA hydrochloride 2,4-benzenetriol,5-(2-aminoethyl)-hydrochloride 6-Hydroxydopamine hy 2,4,5-Trihydroxyphenethylaminehydochloride 2,5-DIHYDROXYTYRAMINE HYDROCHLORIDE 2,4,5-TrihydroxyphenethylamineHCl 5-(2-aminoethyl)-1,2,4-benzenetriolhydrochloride OxidopaMine Hydrochloride Neuro-2a cells,p-p38,Interleukin Related,p38 MAPK,PC12 cells,Apoptosis,Dopamine Rector,Mitophagy,neurotoxicity,Autophagy,Oxidopamine hydrochloride,6-OHDA,Prostaglandin E synthase,Cyclooxygenase,Lesch-Nyhan syndrome,inhibit,Mitochondrial Autophagy,PGE2,attention-deficit hyperactivity disorder,Pkinson’s disease,SH-SY5Y cells,Oxidopamine,Caspase,PGE synthase,Inhibitor,COX,6-Hydroxydopamine TopaMine Hydrochloride 2,4,5-TRIHYDROXYPHENETHYLAMINE HYDROCHLORIDE 2,4,5-Trihydroxyphenethylamine hydrochloride, 2,5-Dihydroxytyramine hydrochloride, 2-(2,4,5-Trihydroxyphenyl)ethylamine hydrochloride, 6-OHDA 4-(2-Aminoethyl)-1,2,3-benzenetriol hydrochloride 6-Hd HCl Nsc233898 6-HYDROXYDOPAMINE HYDROCHLORIDE OxydopaMine HCL Oxidopamine hydrochloride (6-Hydroxydopamine hydrochloride) Oxidopamine (hydrochloride) 5-(2-aMinoethyl)benzene-1,2,4-triol hydrochloride 6-Hydroxydopamine hydrochloride 5-(2-aminoethyl)-4-hydroxypyrocatechol hydrochloride TIMTEC-BB SBB003496 6-hydroxydopaminechloride

Description	Oxidopamine hydrochloride is a neurotoxic synthetic organic compound, selectively destroys dopaminergic and noradrenergic neurons in the brain.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor Research Areas >> Neurological Disease

Boiling Point	406ºC at 760 mmHg
Melting Point	232-233ºC (dec.)(lit.)
Molecular Formula	C₈H₁₂ClNO₃
Molecular Weight	205.63900
Flash Point	199.3ºC
Exact Mass	205.05100
PSA	86.71000
LogP	1.80690
Vapour Pressure	3.58E-07mmHg at 25°C
Storage condition	2-8℃

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DC4650000

CHEMICAL NAME :: 1,2,4-Benzenetriol, 5-(2-aminoethyl)-, hydrochloride

CAS REGISTRY NUMBER :: 28094-15-7

LAST UPDATED :: 199609

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C8-H11-N-O3.Cl-H

MOLECULAR WEIGHT :: 205.66

WISWESSER LINE NOTATION :: Z2R BQ CQ DQ &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 100 mg/kg/52W-I

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Liver - tumors Tumorigenic - tumors at site of application

REFERENCE :: RCOCB8 Research Communications in Chemical Pathology and Pharmacology. (PJD Pub. Ltd., P.O. Box 966, Westbury, NY 11590) V.1- 1970- Volume(issue)/page/year: 17,411,1977

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi: Irritant;
Risk Phrases	R36/37/38
RIDADR	NONH for all modes of transport
RTECS	DC4650000

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