104774-87-0

104774-87-0 structure

Name: Cinacalcet metabolite M4
Chemical Name: 3-[3-(trifluoromethyl)phenyl]propan-1-amine
CAS Number: 104774-87-0
Molecular Formula: C₁₀H₁₂F₃N
Molecular Weight: 203.204
Catalog: Research Areas Cardiovascular Disease
Create Date: 2017-08-29 08:43:56
Modify Date: 2025-08-22 19:58:20
Cinacalcet metabolite M4 is a metabolite of Cinacalcet. Cinacalcet is an orally active, allosteric agonist of Ca receptor (CaR), used for cardiovascular disease[1][2].

Name	3-[3-(trifluoromethyl)phenyl]propan-1-amine
Synonyms	3-[3-(Trifluoromethyl)phenyl]-1-propanamine Benzenepropanamine, 3-(trifluoromethyl)-

Description	Cinacalcet metabolite M4 is a metabolite of Cinacalcet. Cinacalcet is an orally active, allosteric agonist of Ca receptor (CaR), used for cardiovascular disease[1][2].
Related Catalog	Research Areas >> Cardiovascular Disease
References	[1]. Kumar GN, et al. Metabolism and disposition of calcimimetic agent cinacalcet HCl in humans and animalmodels. Drug Metab Dispos. 2004 Dec;32(12):1491-500. [2]. Bushinsky DA, et al. Effect of cinacalcet on urine calcium excretion and supersaturation in genetic hypercalciuric stone-forming rats. Kidney Int. 2006 May;69(9):1586-92.

Hazard Codes	Xi
HS Code	2921499090

535-53-5

~66%

104774-87-0

60689-14-7

104774-87-0

Literature: Tetrahedron Letters, , vol. 45, # 45 p. 8355 - 8358

64380-24-1

104774-87-0

Literature: Tetrahedron Letters, , vol. 45, # 45 p. 8355 - 8358

93040-58-5

104774-87-0

Literature: Bioorganic and Medicinal Chemistry, , vol. 5, # 8 p. 1675 - 1683

779-89-5

104774-87-0

Literature: Bioorganic and Medicinal Chemistry, , vol. 5, # 8 p. 1675 - 1683

HS Code	2921499090
Summary	2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%