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120638-55-3

120638-55-3 structure
120638-55-3 structure
  • Name: bromfenac sodium salt sesquihydrate
  • Chemical Name: bromfenac sodium salt sesquihydrate
  • CAS Number: 120638-55-3
  • Molecular Formula: C15H12BrNO3.3/2H2O.Na
  • Molecular Weight: 383.17
  • Catalog: Research Areas Inflammation/Immunology
  • Create Date: 2018-07-16 19:03:11
  • Modify Date: 2024-01-03 15:17:20
  • Bromfenac (sodium hydrate) is a nonsteroidal anti-inflammatory drug (NSAID), which has anti-inflammatory activity(1) Bromfenac (sodium hydrate) (1 mg/kg, i.v.) is metabolited into an unusual conjugate, bromfenac N-glucoside, in rats bile(2) Bromfenac (sodium hydrate) permeation was found to be 1.62-fold higher through ChS-CS-NPs

Name bromfenac sodium salt sesquihydrate
Synonyms Sodium (2-amino-3-(4-bromobenzoyl)phenyl)acetate
bromfenacum [INN_la]
Bromfenac monosodium salt sesquihydrate
Unii-8ecv571Y37
[2-Amino-3-(4-bromobenzoyl)phenyl]acetic acid
BroMfenac sodiuM 1.5H2O
Bromfenac Sodium Sesquihydrate
Bromfenac ophthalmic
Bromfenac ophthalmic solution
Benzeneacetic acid, 2-amino-3-(4-bromobenzoyl)-
bromfenac
Bromfenac sodium
Duract
Bromfenac (sodium hydrate)
Description Bromfenac (sodium hydrate) is a nonsteroidal anti-inflammatory drug (NSAID), which has anti-inflammatory activity(1) Bromfenac (sodium hydrate) (1 mg/kg, i.v.) is metabolited into an unusual conjugate, bromfenac N-glucoside, in rats bile(2) Bromfenac (sodium hydrate) permeation was found to be 1.62-fold higher through ChS-CS-NPs
Related Catalog
References

[1]. Kirkman SK et al. Isolation and identification of bromfenac glucoside from rat bile. Drug Metab Dispos. 1998 Jul;26(7):720-3.

[2]. Abdullah TA et al. Chondroitin sulfate-chitosan nanoparticles for ocular delivery of bromfenac sodium: Improved permeation, retention, and penetration. Int J Pharm Investig. 2016 Apr-Jun;6(2):96-105.

Density 1.6±0.1 g/cm3
Boiling Point 562.2±50.0 °C at 760 mmHg
Molecular Formula C15H12BrNO3.3/2H2O.Na
Molecular Weight 383.17
Flash Point 293.8±30.1 °C
PSA 80.39000
LogP 2.72
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.663
Storage condition 2-8℃