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102130-84-7

102130-84-7 structure
102130-84-7 structure
  • Name: Nemadectin
  • Chemical Name: Nemadectin
  • CAS Number: 102130-84-7
  • Molecular Formula: C36H52O8
  • Molecular Weight: 612.793
  • Catalog: Research Areas Infection
  • Create Date: 2018-02-08 08:00:00
  • Modify Date: 2024-01-08 15:07:52
  • Nemadectin (CL-287088), an orally active broad-spectrum endectocide, is highly efficacious against natural infections of all the major canine gastrointestinal helminthes. Anthelmintic activity[1].

Name Nemadectin
Synonyms F 28249a
AC-088
(1'R,2R,4S,4'S,5S,6S,8'R,10'E,13'R,14'E,16'E,20'R,21'R,24'S)-4,21',24'-Trihydroxy-5,11',13',22'-tetramethyl-6-[(2E)-4-methyl-2-penten-2-yl]-3,4,5,6-tetrahydro-2'H-spiro[pyran-2,6'-[3,7,19]trioxatetrac ;yclo[15.6.1.1.0]pentacosa[10,14,16,22]tetraen]-2'-one
Antibiotic S-541A
S541 Factor D
LL F-28249a
(6R,23S,25S)-5-O-Demethyl-28-deoxy-25-[(E)-1,3-dimethyl-1-butenyl]-6,28-epoxy-23-hydroxymilbemycin B
Description Nemadectin (CL-287088), an orally active broad-spectrum endectocide, is highly efficacious against natural infections of all the major canine gastrointestinal helminthes. Anthelmintic activity[1].
Related Catalog
In Vivo Nemadectin is highly effective at 0.6 mg/kg BW against natural infections of all major species of canine intestinal helminths, when administered as a single oral dose, either as a liquid or a tablet[1].
References

[1]. Doscher ME, et al. Efficacy of nemadectin, a new broad-spectrum endectocide, against natural infections of canine gastrointestinal helminths. Vet Parasitol. 1989;34(3):255-259.

Density 1.2±0.1 g/cm3
Boiling Point 789.4±60.0 °C at 760 mmHg
Molecular Formula C36H52O8
Molecular Weight 612.793
Flash Point 243.8±26.4 °C
Exact Mass 612.366211
PSA 114.68000
LogP 7.09
Vapour Pressure 0.0±6.2 mmHg at 25°C
Index of Refraction 1.579
Precursor  0

DownStream  1