78816-67-8

78816-67-8 structure

78816-67-8 structure

Name: Bonnecor
Chemical Name: Bonnecor
CAS Number: 78816-67-8
Molecular Formula: C₂₁H₂₆ClN₃O₃
Molecular Weight: 403.90200
Create Date: 2019-01-01 16:05:10
Modify Date: 2024-02-02 16:33:48

Name	Bonnecor
Synonyms	Ethyl (5-((dimethylamino)acetyl)-10,11-dihydro-5H-dibenz(B,F)azepin-3-yl)carbamate monohydrochloride Carbamic acid,(5-((dimethylamino)acetyl)-10,11-dihydro-5H-dibenz(B,F)azepin-3-yl)-,ethyl ester,monohydrochloride TIRACIZINEHYDROCHLORIDE AWD-19-166 Tiracizine Hydrochioride 3-Carbethoxyamino-5-dimethylaminoacetyl-10,11-dihydrodibenz(B,F)azepine hydrochloride GS-015 5H-Dibenz(B,F)azepine-3-carbamic acid,10,11-dihydro-5-((dimethylamino)acetyl)-,ethyl ester,monohydrochloride 3-Carbethoxyamino-5-dimethylaminoacetyl-iminodibenzyle-Hydrochlorid

Boiling Point	525.3ºC at 760 mmHg
Molecular Formula	C₂₁H₂₆ClN₃O₃
Molecular Weight	403.90200
Flash Point	271.5ºC
Exact Mass	403.16600
PSA	61.88000
LogP	4.51990

CHEMICAL IDENTIFICATION

RTECS NUMBER :: HN8110000

CHEMICAL NAME :: 5H-Dibenz(b,f)azepine-3-carbamic acid, 10,11-dihydro-5-((dimethylamino)acetyl)-, ethyl ester, monohydrochloride

CAS REGISTRY NUMBER :: 78816-67-8

LAST UPDATED :: 199803

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C21-H25-N3-O3.Cl-H

MOLECULAR WEIGHT :: 403.95

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 78 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - effect, not otherwise specified Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia

REFERENCE :: PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 40,871,1985

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 10900 ug/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - effect, not otherwise specified Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia

REFERENCE :: PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 40,871,1985

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 48 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - effect, not otherwise specified Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia

REFERENCE :: PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 40,871,1985

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 5400 ug/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - effect, not otherwise specified Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia

REFERENCE :: PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 40,871,1985

83275-56-3 structure

83275-56-3

~%

78816-67-8 structure

78816-67-8

Literature: Wunderlich; Stark; Carstens; Lohmann; Grizenko; Skoldinov Pharmazie, 1985 , vol. 40, # 12 p. 827 - 830

10464-35-4 structure

10464-35-4

~%

78816-67-8 structure

78816-67-8

Literature: Wunderlich; Stark; Carstens; Lohmann; Grizenko; Skoldinov Pharmazie, 1985 , vol. 40, # 12 p. 827 - 830

Precursor 2
83275-56-3 10464-35-4
DownStream 0