128470-15-5

128470-15-5 structure

Name: Melarsomine
Chemical Name: 2-N-[4-[bis(2-aminoethylsulfanyl)arsanyl]phenyl]-1,3,5-triazine-2,4,6-triamine
CAS Number: 128470-15-5
Molecular Formula: C₁₃H₂₁AsN₈S₂
Molecular Weight: 428.41100
Catalog: Research Areas Infection
Create Date: 2018-05-23 08:00:00
Modify Date: 2024-01-05 07:28:25
Melarsomine is a trivalent arsenical compound used as an adulticide. Melarsomine can be used for the reserach of canine heartworm disease and other helminth infections[1][2].

Name	2-N-[4-[bis(2-aminoethylsulfanyl)arsanyl]phenyl]-1,3,5-triazine-2,4,6-triamine
Synonyms	Melarsomine Melarsominum [INN-Latin] Melarsomina Melarsomina [INN-Spanish] Bis(2-aminoethyl) p-((4,6-diamino-s-triazin-2-yl)amino)dithiobenzenearsonite Melarsomine (INN) Melarsominum UNII-374GJ0S41A

Description	Melarsomine is a trivalent arsenical compound used as an adulticide. Melarsomine can be used for the reserach of canine heartworm disease and other helminth infections[1][2].
Related Catalog	Research Areas >> Infection
In Vivo	Melarsomine (2.5 mg/kg; deep i.m. injection) combined with Doramectin managed to clear the D. repens infection in dogs[1]. Melarsomine (0.25 mg/kg; deep i.m. injection) can cure T. evansi infection in camels[2]. Melarsomine (0.5 mg/kg; deep i.m. injection) can cure T. evansi infection in dairy cattle in Thailand[2].
References	[1]. Baneth G, et, al. Dirofilaria repens infection in a dog: diagnosis and treatment with melarsomine and doramectin. Vet Parasitol. 2002 Apr 30;105(2):173-8. [2]. Desquesnes M, et, al. An evaluation of melarsomine hydrochloride efficacy for parasitological cure in experimental infection of dairy cattle with Trypanosoma evansi in Thailand. Parasitology. 2011 Aug;138(9):1134-42.