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  • BioBioPha
  • China
  • Product Name: Thymidine
  • Price: ¥Inquiry/5mg
  • Purity: 98.0%
  • Stocking Period: 10 Day
  • Contact: Xueping-Zheng



50-89-5

50-89-5 structure
50-89-5 structure

Name thymidine
Synonyms 1-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydro-2-furanyl]-5-methyl-2,4(1H,3H)-pyrimidinedione
1-(2-Deoxy-β-D-erythro-pentofuranosyl)-4-hydroxy-5-methyl-2(1H)-pyrimidinone
Thymidine
1-(2-Deoxy-β-D-erythro-pentofuranosyl)-4-hydroxy-5-methylpyrimidin-2(1H)-one
2'-deoxy-5-methyluridine
2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-.β.-D-erythro-pentofuranosyl)-5-methyl-
T6NVMVJ E1 A- ET5OTJ B1Q CQ &&Ribo Form
2,4(1H,3H)-Pyrimidinedione,1-(2-deoxy-.Beta.-D-erythro-pentofuranosyl)-5-methyl
SS-THYMIDINE
2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-β-D-erythro-pentofuranosyl)-5-methyl-
Thyminedeoxyriboside
2'-dT
1-(2-Deoxy-b-D-ribofuranosyl)-5-methyluracil
Zidovudine Related Compound D
EINECS 200-070-4
deoxyribosylthymine
deoxythymidine
DTHD
1-(2-Deoxy-β-D-ribofuranosyl)-5-methyluracil
Thymine-2-deoxyriboside
1-(2-Deoxy-β-D-erythro-pentofuranosyl)-5-methylpyrimidin-2,4(1H,3H)-dion
2'-Deoxythymidine
Thymine deoxyriboside
2(1H)-pyrimidinone, 1-(2-deoxy-β-D-erythro-pentofuranosyl)-4-hydroxy-5-methyl-
3,4-Dihydrothymidine, 2'-deoxy-
2'-deoxy-5-methyl-Uridine
5-Methyldeoxyuridine
3H-Thymidine
1-(2-Deoxy-b-D-erythro-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione
Dthyd
1-(2-Deoxy-β-D-ribofuranosyl)thymine
MFCD00006537
5-methyl-2'-deoxyuridine
b-Thymidine
Thymidin
Description Thymidine is a a pyrimidine deoxynucleoside.
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Cavanagh BL, et al. Thymidine analogues for tracking DNA synthesis. Molecules. 2011 Sep 15;16(9):7980-93.

Density 1.6±0.1 g/cm3
Boiling Point 510.1±60.0 °C at 760 mmHg
Melting Point 187-189ºC
Molecular Formula C10H14N2O5
Molecular Weight 242.229
Flash Point 262.3±32.9 °C
Exact Mass 242.090271
PSA 104.55000
LogP -0.90
Vapour Pressure 0.0±3.0 mmHg at 25°C
Index of Refraction 1.674

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XP2071000
CHEMICAL NAME :
Thymidine
CAS REGISTRY NUMBER :
50-89-5
LAST UPDATED :
199710
DATA ITEMS CITED :
28
MOLECULAR FORMULA :
C10-H14-N2-O5
MOLECULAR WEIGHT :
242.26
WISWESSER LINE NOTATION :
T6NVMVJ E1 A- ET5OTJ B1Q CQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2512 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - changes in motor activity (specific assay)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
400 mg/kg
SEX/DURATION :
female 11 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - musculoskeletal system
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
20 gm/kg
SEX/DURATION :
male 5 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Parenteral
DOSE :
800 mg/kg
SEX/DURATION :
female 8 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
TYPE OF TEST :
Micronucleus test
TYPE OF TEST :
Unscheduled DNA synthesis
TYPE OF TEST :
DNA inhibition
TYPE OF TEST :
Cytogenetic analysis
TYPE OF TEST :
Sperm Morphology

MUTATION DATA

TYPE OF TEST :
DNA damage
TEST SYSTEM :
Mammal - species unspecified Lymphocyte
DOSE/DURATION :
150 mmol/L
REFERENCE :
PNASA6 Proceedings of the National Academy of Sciences of the United States of America. (National Academy of Sciences, Printing & Pub. Office, 2101 Constitution Ave., Washington, DC 20418) V.1- 1915- Volume(issue)/page/year: 48,686,1962 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7245 No. of Facilities: 213 (estimated) No. of Industries: 2 No. of Occupations: 3 No. of Employees: 578 (estimated) No. of Female Employees: 141 (estimated)
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi: Irritant;
Risk Phrases R20/21/22
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS XP2071000