15991-13-6

15991-13-6 structure

Name: Methyl 2-(7-hydroxy-2-oxo-2H-chromen-4-yl)acetate
Chemical Name: methyl 2-(7-hydroxy-2-oxochromen-4-yl)acetate
CAS Number: 15991-13-6
Molecular Formula: C₁₂H₁₀O₅
Molecular Weight: 234.20500
Catalog: Research Areas Others
Create Date: 2016-11-06 15:53:54
Modify Date: 2024-01-23 12:41:35
Methyl 2-(7-hydroxy-2-oxo-2H-chromen-4-yl)acetate, a natural coumarins derivative, is exploited for the synthesis of the switchable fluorescent substrates to be used in bacterial enzyme detection[1][2][3].

Name	methyl 2-(7-hydroxy-2-oxochromen-4-yl)acetate
Synonyms	methyl 2-(7-hydroxy-2-oxo-2H-chromen-4-yl)acetate methyl (7-hydroxy-2-oxo-2H-chromen-4-yl)acetate (7-Hydroxy-2-oxo-2H-chromen-4-yl)-acetic acid methyl ester 7-hydroxy-4-methoxycarbonylmethyl-2H-chromen-2-one methyl 2-(7-hydroxy-2-oxochromen-4-yl) acetate (7'-hydroxycoumarin-4-yl)acetic acid methyl ester 7-hydroxycoumarin-4-acetic acid methyl ester

Description	Methyl 2-(7-hydroxy-2-oxo-2H-chromen-4-yl)acetate, a natural coumarins derivative, is exploited for the synthesis of the switchable fluorescent substrates to be used in bacterial enzyme detection[1][2][3].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	Methyl 2-(7-hydroxy-2-oxo-2H-chromen-4-yl)acetate (compound 2) exhibits the maximum absorption (λabs~322 nm) and emission (λem~387 nm) wavelengths[2].
References	[1]. Nascimento JSD, et al. Mapping the Biotransformation of Coumarins through Filamentous Fungi. Molecules. 2019 Sep 29;24(19). [2]. Lizzul-Jurse A, et al. Readily functionalizable phosphonium-tagged fluorescent coumarins for enhanced detection of conjugates by mass spectrometry. Org Biomol Chem. 2016 Aug 10;14(32):7777-91. [3]. Giovannini G, et al. Coumarin-based, switchable fluorescent substrates for enzymatic bacterial detection. Talanta. 2018 Oct 1;188:448-453.

HS Code	2932209090

67-56-1

6950-82-9

~96%

15991-13-6

1830-54-2

108-46-3

~91%

15991-13-6

Literature: Smitha; Reddy, Ch. Sanjeeva Synthetic Communications, 2004 , vol. 34, # 21 p. 3997 - 4003

1830-54-2

108-46-3

~60%

15991-13-6

780821-74-1

Literature: Dubovik; Garazd; Khilya Chemistry of Heterocyclic Compounds, 2007 , vol. 43, # 3 p. 277 - 281

542-05-2

15991-13-6

Literature: Brubaker; DeRuiter; Whitmer Journal of Medicinal Chemistry, 1986 , vol. 29, # 6 p. 1094 - 1099

108-46-3

15991-13-6

Literature: Baker et al. Journal of the Chemical Society, 1950 , p. 170,172

77-92-9

15991-13-6

Literature: Baker et al. Journal of the Chemical Society, 1950 , p. 170,172

608529-85-7

15991-13-6

HS Code	2932209090
Summary	2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%