Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Ethyl 6,7,8-trifluoro-1,4-dihydro-4-oxoquinoline
Price: ￥266.0/25g ￥796.0/100g ￥136.0/10g ￥76.0/5g
Purity: 95.0%
Stocking Period: 1 Day
Contact: Liu jia

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Ethyl 6,7,8-trifluoro-1,4-dihydro-4-oxoquinoline
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

79660-46-1

79660-46-1 structure

79660-46-1 structure

Name: Ethyl 6,7,8-trifluoro-1,4-dihydro-4-oxoquinoline
Chemical Name: ethyl 6,7,8-trifluoro-4-oxo-1H-quinoline-3-carboxylate
CAS Number: 79660-46-1
Molecular Formula: C₁₂H₈F₃NO₃
Molecular Weight: 271.19200
Catalog: Pharmaceutical intermediate Heterocyclic compound Quinoline compound
Create Date: 2018-12-11 02:10:44
Modify Date: 2024-01-02 12:10:47

Name	ethyl 6,7,8-trifluoro-4-oxo-1H-quinoline-3-carboxylate
Synonyms	6,7,8-trifluoro-4-quinolone-3-carboxylic acid ethyl ester 6,7,8-Triacetoxy-cumarin ethyl 6,7,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate ethyl 6,7,8-trifluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylate 6,7,8-trifluoro-1,4-dihydro-4-oxo-3-quinoline carboxylic acid ethyl ester ethyl 6,7,8-trifluoro-1,4-dihydro-4-oxoquinoline-3-carboxylate 2H-1-Benzopyran-2-one,6,7,8-tris(acetyloxy) MFCD00276021 6,7,8-triacetoxy-coumarin

Density	1.451 g/cm3
Boiling Point	344.3ºC at 760 mmHg
Melting Point	275ºC (dec.)(lit.)
Molecular Formula	C₁₂H₈F₃NO₃
Molecular Weight	271.19200
Flash Point	162ºC
Exact Mass	271.04600
PSA	59.16000
LogP	2.12210

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VB2009830

CHEMICAL NAME :: 3-Quinolinecarboxylic acid, 1,4-dihydro-4-oxo-6,7,8-trifluoro-, ethyl ester

CAS REGISTRY NUMBER :: 79660-46-1

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C12-H8-F3-N-O3

MOLECULAR WEIGHT :: 271.21

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990- Volume(issue)/page/year: 1,83,1990 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990- Volume(issue)/page/year: 1,83,1990

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H319
Precautionary Statements	P305 + P351 + P338
Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi: Irritant;
Risk Phrases	R36/37/38
Safety Phrases	26-36
RIDADR	NONH for all modes of transport
WGK Germany	2
RTECS	VB2009830
HS Code	2933499090

100501-60-8 structure

100501-60-8

~85%

79660-46-1 structure

79660-46-1

Literature: Synthetic Communications, , vol. 39, # 24 p. 4375 - 4383

147694-57-3 structure

147694-57-3

~18%

79660-46-1 structure

79660-46-1

147694-55-1 structure

147694-55-1

Literature: Journal of Organic Chemistry, , vol. 60, # 12 p. 3928 - 3930

143364-59-4 structure

143364-59-4

~%

79660-46-1 structure

79660-46-1

143364-60-7 structure

143364-60-7

Literature: Tetrahedron Letters, , vol. 33, # 26 p. 3733 - 3736

3862-73-5 structure

3862-73-5

~%

79660-46-1 structure

79660-46-1

Literature: Tetrahedron, , vol. 63, # 9 p. 2093 - 2097

1132814-55-1 structure

1132814-55-1

~%

79660-46-1 structure

79660-46-1

Literature: Bioorganic and Medicinal Chemistry, , vol. 20, # 3 p. 1188 - 1200

103995-33-1 structure

103995-33-1

~%

79660-46-1 structure

79660-46-1

Literature: Tetrahedron Letters, , vol. 33, # 26 p. 3733 - 3736

94714-58-6 structure

94714-58-6

~%

79660-46-1 structure

79660-46-1

Literature: Bioorganic and Medicinal Chemistry, , vol. 20, # 3 p. 1188 - 1200

94695-50-8 structure

94695-50-8

~%

79660-46-1 structure

79660-46-1

Literature: Bioorganic and Medicinal Chemistry, , vol. 20, # 3 p. 1188 - 1200

87-13-8 structure

87-13-8

~%

79660-46-1 structure

79660-46-1

Literature: European Journal of Medicinal Chemistry, , vol. 46, # 4 p. 1232 - 1244

Precursor 6
100501-60-8 3862-73-5 1132814-55-1 103995-33-1
94695-50-8 87-13-8
DownStream 4
207231-24-1 75338-42-0 100501-62-0 75338-41-9

HS Code	2933499090
Summary	2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%