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1435-55-8

1435-55-8 structure
1435-55-8 structure

Name Hydroquinidine
Synonyms EINECS 215-862-5
HYDROQUINIDINE
(9S)-6'-Methoxy-10,11-dihydrocinchonan-9-ol
MFCD00135599
(+)-Dihydroquinidine
(9S)-10,11-Dihydro-6'-methoxycinchonan-9-ol
Cinchonan-9-ol, 10,11-dihydro-6'-methoxy-, (9S)-
dihydroquinidine
hydroconchinine
Description Hydroquinidine is an antiarrhythmic agent.
Related Catalog
Density 1.2±0.1 g/cm3
Boiling Point 498.4±30.0 °C at 760 mmHg
Melting Point 169-170 ºC
Molecular Formula C20H26N2O2
Molecular Weight 326.433
Flash Point 255.2±24.6 °C
Exact Mass 326.199432
PSA 45.59000
LogP 3.77
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.626

CHEMICAL IDENTIFICATION

RTECS NUMBER :
MX3016000
CHEMICAL NAME :
Hydroquinidine
CAS REGISTRY NUMBER :
1435-55-8
LAST UPDATED :
199607
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C20-H26-N2-O2
MOLECULAR WEIGHT :
326.48

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human - woman
DOSE/DURATION :
12 mg/kg
TOXIC EFFECTS :
Behavioral - hallucinations, distorted perceptions Behavioral - headache Cardiac - EKG changes not diagnostic of specified effects
REFERENCE :
CTOXAO Clinical Toxicology. (New York, NY) V.1-18, 1968-81. For publisher information, see JTCTDW. Volume(issue)/page/year: 18,659,1981
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
56500 ug/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 84,184,1945
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302 + H312 + H332
Precautionary Statements P280
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn
Risk Phrases 20/21/22
Safety Phrases 36/37-36
RIDADR UN 1544
WGK Germany 3
RTECS MX3016000
Packaging Group III
HS Code 2933990090

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1435-55-8 structure

1435-55-8

Literature: Chemische Berichte, , vol. 45, p. 3317
HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%