83709-73-3
83709-73-3 structure
- Name: 12(S)-Leukotriene B4
- Chemical Name: 12-epi-leukotriene B4
- CAS Number: 83709-73-3
- Molecular Formula: C20H32O4
- Molecular Weight: 336.466
- Create Date: 2017-07-13 13:20:59
- Modify Date: 2024-01-14 15:33:35
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Compared to LTB4, 12-epi LTB4 has significantly reduced activity for the LTB4 receptor on human neutrophils (IC50 of 7.5 mM),2 and on guinea pig lung membranes
| Name | 12-epi-leukotriene B4 |
|---|---|
| Synonyms |
(5S,12S)-dihydroxy-(6E,8E,10E,14Z)-*eicosatetraen
(5S,6Z,8E,10E,12S,14Z)-5,12-Dihydroxy-6,8,10,14-icosatetraenoic acid (5S,12R)-6-trans-leukotriene B 12-epi Leukotriene B4 5(S),12(S)-DIHYDROXYEICOSA-6E,8E,10E,14Z-TETRAENOIC ACID (5S,12S)-DIHYDROXY-(6E,8E,10E,14Z)-EICOS ATETRAENOI 6E-12-EPI-LEUKOTRIENE B4 6(E),5(S),12(R)-leukotriene B4 (5S,6E,8E,10E,12S,14Z)-5,12-Dihydroxy-6,8,10,14-icosatetraenoic acid 6,8,10,14-Eicosatetraenoic acid, 5,12-dihydroxy-, (5S,6Z,8E,10E,12S,14Z)- 5(S),12(S)-DIHETE (5S,12S,6E,8E,10E,14Z)-5,12-Dihydroxy-6,8,10,14-icosatetraenoic acid 6-TRANS-12-EPI-LTB4 (5S,12R,6E,8E,10E,14Z)-5,12-dihydroxy-6,8,10,14-eicosatetraenoic acid |
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 536.4±50.0 °C at 760 mmHg |
| Molecular Formula | C20H32O4 |
| Molecular Weight | 336.466 |
| Flash Point | 292.3±26.6 °C |
| Exact Mass | 336.230072 |
| PSA | 77.76000 |
| LogP | 4.06 |
| Vapour Pressure | 0.0±3.2 mmHg at 25°C |
| Index of Refraction | 1.527 |
| HS Code | 2918199090 |
|---|
| HS Code | 2918199090 |
|---|---|
| Summary | 2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0% |