681135-77-3

681135-77-3 structure

Name: OL-135
Chemical Name: 7-Phenyl-1-[5-(2-pyridinyl)-1,3-oxazol-2-yl]-1-heptanone
CAS Number: 681135-77-3
Molecular Formula: C₂₁H₂₂N₂O₂
Molecular Weight: 334.41200
Create Date: 2016-01-14 22:00:03
Modify Date: 2026-07-16 23:19:09
OL-135 is a CNS penetrant, highly potent and selective reversible inhibitor of FAAH. OL-135 exhibits analgesic pharmacology in various animal models without the motor impairment associated with direct CB1 agonism.

Name	7-Phenyl-1-[5-(2-pyridinyl)-1,3-oxazol-2-yl]-1-heptanone
Synonyms	7-Phenyl-1-[5-(2-pyridinyl)-2-oxazolyl]-1-htanone 7-phenyl-1-(5-pyridin-2-yl-1,3-oxazol-2-yl)htan-1-one 1-Htanone, 7-phenyl-1-[5-(2-pyridinyl)-2-oxazolyl] 7-<2-Hydroxy-aethoxy>-4-nitro-benzofuroxan 1-Oxo-1-[5-(2-pyridyl)oxazol-2-yl]-7-phenylhtane

Molecular Formula	C₂₁H₂₂N₂O₂
Molecular Weight	334.41200
Exact Mass	334.16800
PSA	55.99000
LogP	5.11250

Hazard Statements	H413
RIDADR	NONH for all modes of transport

7472-43-7

681135-77-3

Literature: Pippel, Daniel J.; Mapes, Christopher M.; Mani, Neelakandha S. Journal of Organic Chemistry, 2007 , vol. 72, # 15 p. 5828 - 5831

3580-38-9

681135-77-3

Literature: Pippel, Daniel J.; Mapes, Christopher M.; Mani, Neelakandha S. Journal of Organic Chemistry, 2007 , vol. 72, # 15 p. 5828 - 5831

40228-90-8

681135-77-3

Literature: Pippel, Daniel J.; Mapes, Christopher M.; Mani, Neelakandha S. Journal of Organic Chemistry, 2007 , vol. 72, # 15 p. 5828 - 5831

1121-60-4

681135-77-3

Literature: Pippel, Daniel J.; Mapes, Christopher M.; Mani, Neelakandha S. Journal of Organic Chemistry, 2007 , vol. 72, # 15 p. 5828 - 5831

134511-26-5

681135-77-3

Literature: Pippel, Daniel J.; Mapes, Christopher M.; Mani, Neelakandha S. Journal of Organic Chemistry, 2007 , vol. 72, # 15 p. 5828 - 5831

70380-73-3

61875-55-6

~65%

681135-77-3

Literature: Boger, Dale L.; Miyauchi, Hiroshi; Du, Wu; Hardouin, Christophe; Fecik, Robert A.; Cheng, Heng; Hwang, Inkyu; Hedrick, Michael P.; Leung, Donmienne; Acevedo, Orlando; Guimaraes, Cristiano R. W.; Jorgensen, William L.; Cravatt, Benjamin F. Journal of Medicinal Chemistry, 2005 , vol. 48, # 6 p. 1849 - 1856

Precursor 7
7472-43-7 3580-38-9 40228-90-8 1121-60-4
134511-26-5 70380-73-3 61875-55-6
DownStream 0

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