1100353-03-4
1100353-03-4 structure
- Name: Procaspase-3 activator 1541
- Chemical Name: N-[3-(Imidazo[1,2-a]pyridin-2-yl)phenyl]-8-methoxy-2-oxo-2H-chrom ene-3-carboxamide
- CAS Number: 1100353-03-4
- Molecular Formula: C24H17N3O4
- Molecular Weight: 411.41
- Catalog: Signaling Pathways Apoptosis Caspase
- Create Date: 2016-09-27 11:27:54
- Modify Date: 2024-01-11 17:19:40
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Procaspase-3/6 activator 1 (compound 1541) is a highly specific and robust activator of executioner procaspases-3 and -6, with EC50 values of 2.4 ± 0.2 and 2.8 ± 0.3 μM, respectively. Procaspase-3/6 activator 1 does not activate procaspases-1 or -7[1].
| Name | N-[3-(Imidazo[1,2-a]pyridin-2-yl)phenyl]-8-methoxy-2-oxo-2H-chrom ene-3-carboxamide |
|---|---|
| Synonyms | Procaspase-3 activator 1541 |
| Description | Procaspase-3/6 activator 1 (compound 1541) is a highly specific and robust activator of executioner procaspases-3 and -6, with EC50 values of 2.4 ± 0.2 and 2.8 ± 0.3 μM, respectively. Procaspase-3/6 activator 1 does not activate procaspases-1 or -7[1]. |
|---|---|
| Related Catalog | |
| Target |
Procaspase-3:2.4 ± 0.2 μM (EC50) Procaspase-6:2.8 ± 0.3 μM (EC50) |
| References |
[1]. Wolan DW, et al. Small-molecule activators of a proenzyme. Science. 2009 Nov 6;326(5954):853-8. |
| Molecular Formula | C24H17N3O4 |
|---|---|
| Molecular Weight | 411.41 |
| Exact Mass | 411.12200 |
| PSA | 85.84000 |
| LogP | 4.44160 |
| Storage condition | 2-8°C |