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Product Name: Hydracarbazine
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3614-47-9

3614-47-9 structure

3614-47-9 structure

Name: Hydracarbazine
Chemical Name: 6-hydrazinylpyridazine-3-carboxamide
CAS Number: 3614-47-9
Molecular Formula: C₅H₇N₅O
Molecular Weight: 153.14200
Catalog: Research Areas Cardiovascular Disease
Create Date: 2018-09-01 06:34:59
Modify Date: 2024-01-20 22:31:37
Hydracarbazine is a pyridazine. Hydracarbazine can effectively lower blood pressure, it can be used for the research of high blood pressure[1][2].

Name	6-hydrazinylpyridazine-3-carboxamide
Synonyms	3-Hydrazino-6-carbamoyl-pyridazin 6-hydrazinopyridazine-3-carboxamide 6-Hydrazino-pyridazin-3-carbonsaeure-amid Hidracarbazina 6-hydrazino-pyridazine-3-carboxylic acid amide UNII-6CTK2FB9QM TH-2151 Hydracarbazine Hydracarbazinum Hydracarbazine [INN:DCF] 3-carbamoyl-6-pyridazinylhydrazine

Description	Hydracarbazine is a pyridazine. Hydracarbazine can effectively lower blood pressure, it can be used for the research of high blood pressure[1][2].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others
In Vivo	Hydracarbazine (1-4 mg/kg; i.v. once) induced in the dog, cat and rabbit hypotension by peripheral vasodilation, showed no inhibitory action on vasomotor centers and decreased the hypertensive effects of adrenaline, noradrenaline, 5-hydroxytryptamine, pituitrin, and splanchnic nerve stimulation[1]. Hydracarbazine (15-18 mg/kg; p.o. once daily) prevents the increased blood pressure and heart rate, reduces the renal histol and reduces the hypertensive syndrome with a combination of pempidine in high arterial pressure rats[2].
References	[1]. Schmitt H, et al. Pharmacological study of a new hypotensor with a long duration of action: 1-hydrazino-4-carboxamidopyridazine (1325). Journal de Physiologie. 1992 52:525-36. [2]. Ghaye-Roquet J, et al. [Prevention of experimental hypertension in the rat by prolonged administration of a combination of antihypertensive agents]. Arch Int Pharmacodyn Ther. 1967 Mar;166(1):65-78.

Density	1.513g/cm3
Boiling Point	549.1ºC at 760mmHg
Molecular Formula	C₅H₇N₅O
Molecular Weight	153.14200
Flash Point	285.9ºC
Exact Mass	153.06500
PSA	110.15000
Index of Refraction	1.717

HS Code	2933990090

66346-83-6 structure

66346-83-6

~%

3614-47-9 structure

3614-47-9

89280-46-6 structure

89280-46-6

Literature: Libermann; Rouaix Bulletin de la Societe Chimique de France, 1959 , p. 1793,1796

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%