Hydracarbazine

Modify Date: 2024-01-20 22:31:37

Hydracarbazine Structure
Hydracarbazine structure
Common Name Hydracarbazine
CAS Number 3614-47-9 Molecular Weight 153.14200
Density 1.513g/cm3 Boiling Point 549.1ºC at 760mmHg
Molecular Formula C5H7N5O Melting Point N/A
MSDS N/A Flash Point 285.9ºC

 Use of Hydracarbazine


Hydracarbazine is a pyridazine. Hydracarbazine can effectively lower blood pressure, it can be used for the research of high blood pressure[1][2].

 Names

Name 6-hydrazinylpyridazine-3-carboxamide
Synonym More Synonyms

 Hydracarbazine Biological Activity

Description Hydracarbazine is a pyridazine. Hydracarbazine can effectively lower blood pressure, it can be used for the research of high blood pressure[1][2].
Related Catalog
In Vivo Hydracarbazine (1-4 mg/kg; i.v. once) induced in the dog, cat and rabbit hypotension by peripheral vasodilation, showed no inhibitory action on vasomotor centers and decreased the hypertensive effects of adrenaline, noradrenaline, 5-hydroxytryptamine, pituitrin, and splanchnic nerve stimulation[1]. Hydracarbazine (15-18 mg/kg; p.o. once daily) prevents the increased blood pressure and heart rate, reduces the renal histol and reduces the hypertensive syndrome with a combination of pempidine in high arterial pressure rats[2].
References

[1]. Schmitt H, et al. Pharmacological study of a new hypotensor with a long duration of action: 1-hydrazino-4-carboxamidopyridazine (1325). Journal de Physiologie. 1992 52:525-36.

[2]. Ghaye-Roquet J, et al. [Prevention of experimental hypertension in the rat by prolonged administration of a combination of antihypertensive agents]. Arch Int Pharmacodyn Ther. 1967 Mar;166(1):65-78.

 Chemical & Physical Properties

Density 1.513g/cm3
Boiling Point 549.1ºC at 760mmHg
Molecular Formula C5H7N5O
Molecular Weight 153.14200
Flash Point 285.9ºC
Exact Mass 153.06500
PSA 110.15000
Index of Refraction 1.717

 Safety Information

HS Code 2933990090

 Synthetic Route

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Hydracarbazine Structure

Hydracarbazine

CAS#:3614-47-9

Literature: Libermann; Rouaix Bulletin de la Societe Chimique de France, 1959 , p. 1793,1796

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

3-Hydrazino-6-carbamoyl-pyridazin
6-hydrazinopyridazine-3-carboxamide
6-Hydrazino-pyridazin-3-carbonsaeure-amid
Hidracarbazina
6-hydrazino-pyridazine-3-carboxylic acid amide
UNII-6CTK2FB9QM
TH-2151
Hydracarbazine
Hydracarbazinum
Hydracarbazine [INN:DCF]
3-carbamoyl-6-pyridazinylhydrazine
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