Hydracarbazine

Modify Date: 2025-08-27 10:57:18

Hydracarbazine Structure
Hydracarbazine structure
Common Name Hydracarbazine
CAS Number 3614-47-9 Molecular Weight 153.14200
Density 1.513g/cm3 Boiling Point 549.1ºC at 760mmHg
Molecular Formula C5H7N5O Melting Point N/A
MSDS N/A Flash Point 285.9ºC

 Use of Hydracarbazine


Hydracarbazine is a pyridazine. Hydracarbazine can effectively lower blood pressure, it can be used for the research of high blood pressure[1][2].

 Names

Name 6-hydrazinylpyridazine-3-carboxamide
Synonym More Synonyms

 Hydracarbazine Biological Activity

Description Hydracarbazine is a pyridazine. Hydracarbazine can effectively lower blood pressure, it can be used for the research of high blood pressure[1][2].
Related Catalog
In Vivo Hydracarbazine (1-4 mg/kg; i.v. once) induced in the dog, cat and rabbit hypotension by peripheral vasodilation, showed no inhibitory action on vasomotor centers and decreased the hypertensive effects of adrenaline, noradrenaline, 5-hydroxytryptamine, pituitrin, and splanchnic nerve stimulation[1]. Hydracarbazine (15-18 mg/kg; p.o. once daily) prevents the increased blood pressure and heart rate, reduces the renal histol and reduces the hypertensive syndrome with a combination of pempidine in high arterial pressure rats[2].
References

[1]. Schmitt H, et al. Pharmacological study of a new hypotensor with a long duration of action: 1-hydrazino-4-carboxamidopyridazine (1325). Journal de Physiologie. 1992 52:525-36.

[2]. Ghaye-Roquet J, et al. [Prevention of experimental hypertension in the rat by prolonged administration of a combination of antihypertensive agents]. Arch Int Pharmacodyn Ther. 1967 Mar;166(1):65-78.

 Chemical & Physical Properties

Density 1.513g/cm3
Boiling Point 549.1ºC at 760mmHg
Molecular Formula C5H7N5O
Molecular Weight 153.14200
Flash Point 285.9ºC
Exact Mass 153.06500
PSA 110.15000
Index of Refraction 1.717
InChIKey WRYZEGZNBYOMLE-UHFFFAOYSA-N
SMILES NNc1ccc(C(N)=O)nn1

 Safety Information

HS Code 2933990090

 Synthetic Route

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Hydracarbazine Structure

Hydracarbazine

CAS#:3614-47-9

Literature: Libermann; Rouaix Bulletin de la Societe Chimique de France, 1959 , p. 1793,1796

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

3-Hydrazino-6-carbamoyl-pyridazin
6-hydrazinopyridazine-3-carboxamide
6-Hydrazino-pyridazin-3-carbonsaeure-amid
Hidracarbazina
6-hydrazino-pyridazine-3-carboxylic acid amide
UNII-6CTK2FB9QM
TH-2151
Hydracarbazine
Hydracarbazinum
Hydracarbazine [INN:DCF]
3-carbamoyl-6-pyridazinylhydrazine
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