22571-95-5
22571-95-5 structure
- Name: Symphytine
- Chemical Name: symphytine
- CAS Number: 22571-95-5
- Molecular Formula: C20H31NO6
- Molecular Weight: 381.46300
- Catalog: Signaling Pathways Others Others
- Create Date: 2016-05-23 18:47:36
- Modify Date: 2024-01-09 17:52:03
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Symphytine is a pyrrolizidine alkaloid isolated from Symphytum officinale and has carcinogenicity[1].
| Name | symphytine |
|---|---|
| Synonyms |
myoporoside
(1R,7aR)-7-{[(2,3-Dihydroxy-2-isopropylbutanoyl)oxy]methyl}-2,3,5 ,7a-tetrahydro-1H-pyrrolizin-1-yl (2E)-2-methyl-2-butenoate myoscorpine Ajugol |
| Description | Symphytine is a pyrrolizidine alkaloid isolated from Symphytum officinale and has carcinogenicity[1]. |
|---|---|
| Related Catalog | |
| In Vivo | Symphytine (intraperitoneal injection; 13 mg/kg; 330 days) leads to survival for more than 330 days after the start of injections. Four of 20 rats (20%) had liver tumors: three has hemangioendothelial sarcoma and 1 has liver cell adenoma[1]. Animal Model: Male inbred ACI rats[1] Dosage: 13 mg/kg Administration: Intraperitoneal injection; 330 days Result: Led to hepatic tumor in rats. |
| References |
| Molecular Formula | C20H31NO6 |
|---|---|
| Molecular Weight | 381.46300 |
| Exact Mass | 381.21500 |
| PSA | 96.30000 |
| LogP | 1.12770 |
| RIDADR | UN 1544 |
|---|