845745-37-1

845745-37-1 structure

Name: (S)-1-((S)-3,3-DIMETHYL-2-((S)-2-(METHYLAMINO)PROPANAMIDO)BUTANOYL)-N-((R)-1,2,3,4-TETRAHYDRONAPHTHALEN-1-YL)PYRROLIDINE-2-CARBOXAMIDE HYDROCHLORIDE
Chemical Name: (2S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]pyrrolidine-2-carboxamide,hydrochloride
CAS Number: 845745-37-1
Molecular Formula: C₂₅H₃₉ClN₄O₃
Molecular Weight: 479.06
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2016-01-12 12:23:52
Modify Date: 2025-08-22 19:07:21
(S)-SW IV-52 hydrochloride is a small molecule that can induce apoptosis in ovarian cancer. (S)-SW IV-52 hydrochloride has minimal single-agent activity at concentrations up to 200 μM[1].

Name	(2S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]pyrrolidine-2-carboxamide,hydrochloride
Synonyms	(S)-1-((S)-3,3-Dimethyl-2-((S)-2-(methylamino)propanamido)butanoyl)-N-((R)-1,2,3,4-tetrahydronaphthalen-1-yl)pyrrolidine-2-carboxamide hydrochloride

Description	(S)-SW IV-52 hydrochloride is a small molecule that can induce apoptosis in ovarian cancer. (S)-SW IV-52 hydrochloride has minimal single-agent activity at concentrations up to 200 μM[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer
References	[1]. Garg G, et al. Conjugation to a SMAC mimetic potentiates sigma-2 ligand induced tumor cell death in ovarian cancer. Mol Cancer. 2014 Mar 7;13:50.