Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: (3aS)-3aβ,4,5,7,8,9,9aβ,9bα-Octahydro-9β-hydroxy-6,9-dimethyl-3-methyleneazuleno[4,5-b]furan-2(3H)-one
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Purity: 98.0%
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68370-47-8

68370-47-8 structure

Name: Micheliolide
Chemical Name: (3aS,9R,9aS,9bS)-9-hydroxy-6,9-dimethyl-3-methylidene-4,5,7,8,9a,9b-hexahydro-3aH-azuleno[4,5-b]furan-2-one
CAS Number: 68370-47-8
Molecular Formula: C₁₅H₂₀O₃
Molecular Weight: 248.318
Catalog: Research Areas Others
Create Date: 2018-09-26 09:38:57
Modify Date: 2024-01-02 14:09:35
Micheliolide could effectively attenuate the high glucose-stimulated activation of NF-κB, the degradation of IκBα, and the expression of MCP-1, TGF-β1 and FN in rat mesangial cells (MCs).

Name	(3aS,9R,9aS,9bS)-9-hydroxy-6,9-dimethyl-3-methylidene-4,5,7,8,9a,9b-hexahydro-3aH-azuleno[4,5-b]furan-2-one
Synonyms	Azuleno[4,5-b]furan-2(3H)-one, 3a,4,5,7,8,9,9a,9b-octahydro-9-hydroxy-6,9-dimethyl-3-methylene-, (3aS,9R,9aS,9bS)- (3aS,9R,9aS,9bS)-9-Hydroxy-6,9-dimethyl-3-methylene-3a,4,5,7,8,9,9a,9b-octahydroazuleno[4,5-b]furan-2(3H)-one Mecheliolide MICHELIOLIDE

Description	Micheliolide could effectively attenuate the high glucose-stimulated activation of NF-κB, the degradation of IκBα, and the expression of MCP-1, TGF-β1 and FN in rat mesangial cells (MCs).
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Others Natural Products >> Terpenoids and Glycosides
References	[1]. Jia QQ, et al. Sesquiterpene lactones and their derivatives inhibit high glucose-induced NF-κB activation and MCP-1 and TGF-β1 expression in rat mesangial cells. Molecules. 2013 Oct 21;18(10):13061-77.