874638-80-9
874638-80-9 structure
- Name: (2R)-2-Deoxy-2-fluoro-2-methyl-D-erythropentonic acid gamma-lactone 3,5-dibenzoate
- Chemical Name: (2R)-2-Deoxy-2-fluoro-2-methyl-D-erythropentonic acid gamma-lactone 3,5-dibenzoate
- CAS Number: 874638-80-9
- Molecular Formula: C20H17FO6
- Molecular Weight: 372.344
- Catalog: Pharmaceutical intermediate API intermediate
- Create Date: 2018-12-07 10:07:12
- Modify Date: 2026-06-30 12:27:43
| Name | (2R)-2-Deoxy-2-fluoro-2-methyl-D-erythropentonic acid gamma-lactone 3,5-dibenzoate |
|---|---|
| Synonyms |
(2R-3R,4R)-3-(Benzoyzxy)-4-Fluoro-4-Methyl-5-Oxotetrahydrofuran-2Yl)Methyl Benzoate
(2R,3R,4R)-3- (benzoyoxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2yl)methyl Benzoate SofosBuvir Impurity 46 3,5-di-O-benzoyl-2-deoxy-2-fluoro-2-C-methyl-D-ribono-γ-latone ((2R,3S,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate (2R)-2-Deoxy-2-fluoro-2-methyl-D-erythropentonic acid γ-lactone 3,5-dibenzoate (2R) -2-Deoxy-2-Fluoro-2-Methyl-D-Erythropentonic Acid y-Lactone 3,5-Dibenzoate 3,5-Di-O-benzoyl-2-deoxy-2-fluoro-2C-methyl-D-ribono-1,4-lactone 3. ((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-Methyl-5-oxotetra ((2R,3R,4R)-3-(BENZOYLOXY)-4-FLUORO-4-METHYL-5-OXOTETRAHYDROFURAN-2-YL)METHYL BENZOATE 874-9 4-amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]pyrimidin-2-one ((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate ISO 9001：2015 REACH (2R)-2-Deoxy-2-fluoro-2-methy-D- erythropentonic acid gamma-lactone 3,5- dibenzoate Sofosbuvir INT 3 Sofosbuvir Impurity 30 (2R,3R,4R)-3-Benzoyloxy-4-fluoro-4-methyl-5-oxo-2-(benzoyloxymethyl)tetrahydrofuran ((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate Di-O-benzoyl-2-deoxy-2-fluoro-2-C-Methyl-D PSI-6130 interMediate D-erythro-Pentonic acid, 2-deoxy-2-fluoro-2-Methyl-, γ-lactone, 3,5-dibenzoate, (2R) (2R)-2-DEOXY-2-FLUORO-2-METHYL-D-ERYTHRO (2R,3R,4R)-2-[(benzoyloxy)methyl]-4-fluoro-4-methyl-5-oxooxolan-3-yl benzoate SF-X1 Sofosbuvir imp-2 (2R)-2-Deoxy-2-fluoro-2-Methyl-D-erythropentonic acid ((2R,3R,4R)-3-(DENZOYLOXY)-4-FLUORO-4-METHYL-5-OXOTETRAHYDROFURAN-2-YL)METHYL BENZOATE Sofosbuvir Intermediate 1 nterMediate of Sofosbuvir Methyl ((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-Methyl-5-oxotetrahydrofuran-2-yl) benzoate 3,5-di-O-benzoyl-2-deoxy-2-fluoro-D-ribono-γ-latone Sofosbuvir intermediate 3,5-Di-O-benzoyl-2-deoxy-2-fluoro-2C-methyl-D-abino-1,4-lactone 3,5-Di-O-benzoyl-2-deoxy-2-fluoro-2-C-Methyl-D-ribono-γ-lactone (2R)-3,5-di-O-benzoyl-2-fluoro-2-C-methyl-D-ribono-r-lactone (2R)-2-Deoxy-2-fluoro-2-Methyl-D-erythro-pentonic acid-g-lactone 3,5-dibenzoate [(2R,3R,4R)-3-benzoyloxy-4-fluoro-4-methyl-5-oxooxolan-2-yl]methyl benzoate (S)-isopropyl 2-(((S)-(((2R,3R,4R,5S)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate [(2R,3R,4R)-3-(Benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydro-2-furanyl]methyl benzoate ((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydro ((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-5-oxotetrahydrofuran-2-yl)methyl benzoate InterMediate of Sofosbuvir Sofosbuvir Impurity |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 458.6±34.0 °C at 760 mmHg |
| Melting Point | 133℃ |
| Molecular Formula | C20H17FO6 |
| Molecular Weight | 372.344 |
| Flash Point | 222.9±20.6 °C |
| Exact Mass | 372.100922 |
| PSA | 78.90000 |
| LogP | 4.07 |
| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
| Index of Refraction | 1.577 |
| Hazard Codes | Xi |
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|
~89%
874638-80-9 |
| Literature: WO2006/31725 A2, ; Page/Page column 13; 30-31 ; |
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~%
874638-80-9 |
| Literature: US2013/72699 A1, ; |
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874638-80-9 |
| Literature: US2013/72699 A1, ; |
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~%
874638-80-9 |
| Literature: US2013/72699 A1, ; |
| Precursor 5 | |
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| DownStream 1 | |
