74135-04-9
74135-04-9 structure
- Name: β-Casomorphin (1-4) amide (bovine) acetate salt
- Chemical Name: Tyr-Pro-Phe-Pro-NH2
- CAS Number: 74135-04-9
- Molecular Formula: C28H35N5O5
- Molecular Weight: 521.60800
- Catalog: Research Areas Cardiovascular Disease
- Create Date: 2017-04-11 21:15:49
- Modify Date: 2025-08-20 10:34:23
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Morphiceptin is a potent and specific agonist for morphine (μ) receptors. Morphiceptin, as a synthetic peptide, is the amide of a fragment of the milk protein β-casein. Morphiceptin has morphinelike activities and is highly specific for morphine (μ) receptors but not for enkephalin (⸹) receptors[1].
| Name | Tyr-Pro-Phe-Pro-NH2 |
|---|---|
| Synonyms |
Morphiceptin, Beta-Casomorphin (1-4) amide (bovine)
B-CASOMORPHIN (1-4) AMIDE (BOVINE) cis-Morphiceptin Beta-Casomorphin (1-4) amide (bovine).Morphiceptin trans-Morphiceptin morphicetin morphiceptin N-((R)-α-methylbenzyl)-3-aminopropan-1-ol |
| Description | Morphiceptin is a potent and specific agonist for morphine (μ) receptors. Morphiceptin, as a synthetic peptide, is the amide of a fragment of the milk protein β-casein. Morphiceptin has morphinelike activities and is highly specific for morphine (μ) receptors but not for enkephalin (⸹) receptors[1]. |
|---|---|
| Related Catalog | |
| Target |
Morphine (μ) Receptor[1] |
| In Vivo | Morphiceptin potently inhibits the binding of [3H]dihydromorphine, 125I-labeled FK33824, and [3H]naloxone to rat brain membrane preparations with a 50 percent inhibition concentration (IC50) of about 20 nM[1]. |
| References |
| Density | 1.327±0.06 g/cm3(Predicted) |
|---|---|
| Boiling Point | 919.9±65.0 °C(Predicted) |
| Molecular Formula | C28H35N5O5 |
| Molecular Weight | 521.60800 |
| Exact Mass | 521.26400 |
| PSA | 159.06000 |
| LogP | 2.12410 |