β-Casomorphin (1-4) amide (bovine) acetate salt

Modify Date: 2025-08-20 10:34:23

β-Casomorphin (1-4) amide (bovine) acetate salt Structure
β-Casomorphin (1-4) amide (bovine) acetate salt structure
Common Name β-Casomorphin (1-4) amide (bovine) acetate salt
CAS Number 74135-04-9 Molecular Weight 521.60800
Density 1.327±0.06 g/cm3(Predicted) Boiling Point 919.9±65.0 °C(Predicted)
Molecular Formula C28H35N5O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of β-Casomorphin (1-4) amide (bovine) acetate salt


Morphiceptin is a potent and specific agonist for morphine (μ) receptors. Morphiceptin, as a synthetic peptide, is the amide of a fragment of the milk protein β-casein. Morphiceptin has morphinelike activities and is highly specific for morphine (μ) receptors but not for enkephalin (⸹) receptors[1].

 Names

Name Tyr-Pro-Phe-Pro-NH2
Synonym More Synonyms

  Biological Activity

Description Morphiceptin is a potent and specific agonist for morphine (μ) receptors. Morphiceptin, as a synthetic peptide, is the amide of a fragment of the milk protein β-casein. Morphiceptin has morphinelike activities and is highly specific for morphine (μ) receptors but not for enkephalin (⸹) receptors[1].
Related Catalog
Target

Morphine (μ) Receptor[1]

In Vivo Morphiceptin potently inhibits the binding of [3H]dihydromorphine, 125I-labeled FK33824, and [3H]naloxone to rat brain membrane preparations with a 50 percent inhibition concentration (IC50) of about 20 nM[1].
References

[1]. Chang KJ, et al. Morphiceptin (NH4-tyr-pro-phe-pro-COHN2): a potent and specific agonist for morphine (mu) receptors. Science. 1981;212(4490):75-77.

 Chemical & Physical Properties

Density 1.327±0.06 g/cm3(Predicted)
Boiling Point 919.9±65.0 °C(Predicted)
Molecular Formula C28H35N5O5
Molecular Weight 521.60800
Exact Mass 521.26400
PSA 159.06000
LogP 2.12410

 Synonyms

Morphiceptin, Beta-Casomorphin (1-4) amide (bovine)
B-CASOMORPHIN (1-4) AMIDE (BOVINE)
cis-Morphiceptin
Beta-Casomorphin (1-4) amide (bovine).Morphiceptin
trans-Morphiceptin
morphicetin
morphiceptin
N-((R)-α-methylbenzyl)-3-aminopropan-1-ol
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