β-Casomorphin (1-4) amide (bovine) acetate salt

Modify Date: 2024-01-08 17:14:52

β-Casomorphin (1-4) amide (bovine) acetate salt structure	Common Name	β-Casomorphin (1-4) amide (bovine) acetate salt
	CAS Number	74135-04-9	Molecular Weight	521.60800
	Density	1.327±0.06 g/cm3(Predicted)	Boiling Point	919.9±65.0 °C(Predicted)
	Molecular Formula	C₂₈H₃₅N₅O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of β-Casomorphin (1-4) amide (bovine) acetate salt

Morphiceptin is a potent and specific agonist for morphine (μ) receptors. Morphiceptin, as a synthetic peptide, is the amide of a fragment of the milk protein β-casein. Morphiceptin has morphinelike activities and is highly specific for morphine (μ) receptors but not for enkephalin (⸹) receptors[1].

Name	Tyr-Pro-Phe-Pro-NH2
Synonym	More Synonyms

Description	Morphiceptin is a potent and specific agonist for morphine (μ) receptors. Morphiceptin, as a synthetic peptide, is the amide of a fragment of the milk protein β-casein. Morphiceptin has morphinelike activities and is highly specific for morphine (μ) receptors but not for enkephalin (⸹) receptors[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
Target	Morphine (μ) Receptor[1]
In Vivo	Morphiceptin potently inhibits the binding of [3H]dihydromorphine, 125I-labeled FK33824, and [3H]naloxone to rat brain membrane preparations with a 50 percent inhibition concentration (IC50) of about 20 nM[1].
References	[1]. Chang KJ, et al. Morphiceptin (NH4-tyr-pro-phe-pro-COHN2): a potent and specific agonist for morphine (mu) receptors. Science. 1981;212(4490):75-77.

Density	1.327±0.06 g/cm3(Predicted)
Boiling Point	919.9±65.0 °C(Predicted)
Molecular Formula	C₂₈H₃₅N₅O₅
Molecular Weight	521.60800
Exact Mass	521.26400
PSA	159.06000
LogP	2.12410