223611-42-5
223611-42-5 structure
- Name: S-acetyl-PEG4-alcohol
- Chemical Name: S-11-hydroxy-3,6,9-trioxaundecyl ethanethioate
- CAS Number: 223611-42-5
- Molecular Formula: C10H20O5S
- Molecular Weight: 252.32800
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2017-09-12 15:25:33
- Modify Date: 2024-01-05 18:55:53
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S-acetyl-PEG4-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | S-11-hydroxy-3,6,9-trioxaundecyl ethanethioate |
|---|---|
| Synonyms |
11-thioacetate-3,6,9-trioxa-undecan-1-ol
tetraethylene glycol monothioacetate S-acetyl-PEG4-alcohol |
| Description | S-acetyl-PEG4-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Molecular Formula | C10H20O5S |
|---|---|
| Molecular Weight | 252.32800 |
| Exact Mass | 252.10300 |
| PSA | 90.29000 |
| LogP | 0.30820 |
| Precursor 0 | |
|---|---|
| DownStream 1 | |
