18524-94-2

18524-94-2 structure

Name: Loganin
Chemical Name: loganin
CAS Number: 18524-94-2
Molecular Formula: C₁₇H₂₆O₁₀
Molecular Weight: 390.382
Catalog: Biochemical Chinese herbal medicine ingredients
Create Date: 2018-07-14 12:28:02
Modify Date: 2026-06-29 20:20:10
Loganin, a major iridoid glycoside obtained from Corni fructus, has been shown to have anti-inflammatory and anti-shock effects. Loganin exhibits an anti-inflammatory effect in cases of AP and its pulmonary complications through inhibition of NF-κB activation.

Name	loganin
Synonyms	Cyclopenta[c]pyran-4-cboxylic acid, 1-(beta-D-glucopyranosyloxy)-1,4a,5,6,7,7a-hexahydro-6-hydroxy-7-methyl-, methyl ester, [1S-(1alpha,4aalpha,6alpha,7alpha,7aalpha)] (1S,4aS,6S,7R,7aS)-1-(β-D-Glucopyranosyloxy)-6-hydroxy-7-méthyl-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylate de méthyle Loganoside Cuchiloside Loganin //BP methyl (1S,4aS,6S,7R,7aS)-6-hydroxy-7-methyl-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-cboxylate LOGANINE 6-hydroxy-7-methyl-1-[[3,4,5-trihydroxy-6-(hydroxymethyl)-2-oxanyl]oxy]-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-cboxylic acid methyl ester Methyl (1S,4aS,6S,7R,7aS)-6-hydroxy-7-Methyl-1-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxyMethyl)oxan-2-yl]oxy}-1H,4aH,5H,6H,7H,7aH-cyclopenta[c]pyran-4-cboxylate Loganinl Loganin-RM (1S,4aS,6S,7R,7aS)-6-Hydroxy-7-méthyl-1-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxyméthyl)tétrahydro-2H-pyran-2-yl]oxy}-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylate de méthyle methyl [1S-(1alpha,4aalpha,6alpha,7alpha,7a.alpha.)]-1-(beta-D-glucopyranosyloxy)-1,4a,5,6,7,7a-hexahydro-6-hydroxy-7-methylcyclopenta[c]pyran-4-cboxylate Methyl (1S,4aS,6S,7R,7aS)-6-hydroxy-7-methyl-1-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylate Loganin(AS) 1-(b-D-Glucopyranosyloxy)-1,4a,5,6,7,7a-hexahydro-6-hydroxy-7-methylcyclopenta[c]pyran-4-carboxylic Acid Methyl Ester Methyl [1S-(1alpha,4aalpha,6alpha,7alpha,7aalpha)]-1-(beta-D-glucopyranosyloxy)-1,4a,5,6,7,7a-hexahydro-6-hydroxy-7-methylcyclopenta[c]pyran-4-cboxylate (1S,4aS,6S,7R,7aS)-1-(β-D-Glucopyranosyloxy)-1,4a,5,6,7,7a-hexahydro-6-hydroxy-7-Methylcyclopenta[c]pyran-4-cboxylic Acid Methyl Ester Methyl-(1S,4aS,6S,7R,7aS)-6-hydroxy-7-methyl-1-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylat LOGANIN (1S)-1α-(β-D-Glucopyranosyloxy)-1,4aα,5,6,7,7aα-hexahydro-6α-hydroxy-7α-methylcyclopenta[c]pyran-4-cboxylic acid methyl ester LOGANIN(P) Meliatin EINECS 242-398-0 7-HYDROXY-6-DESOXYVERBENALIN (-)-Loganin methyl 1-(beta-D-glucopyranosyloxy)-6-hydroxy-7-methyl-1,4a Methyl (1S,4aS,6S,7R,7aS)-1-(β-D-glucopyranosyloxy)-6-hydroxy-7-methyl-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylate Loganin 18-2 Loganin from Strychnos nux-vomica L MFCD00075645 methyl 1-(beta-D-glucopyranosyloxy)-6-hydroxy-7-methyl-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-c (1S)-1α-(β-D-Glucopyranosyloxy)-6α-hydroxy-7α-methyl-1,4aα,5,6,7,7aα-hexahydrocyclopenta[c]pyran-4-cboxylic acid methyl ester Loganin> loganic acid methyl ester Methyl 6-hydroxy-7-methyl-1-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,4a,5,6,7,7a-hexahydrocyclopenta[d]pyran-4-cboxylate Cyclopenta[c]pyran-4-cboxylicacid, 1-(b-D-glucopyranosyloxy)-1,4a,5,6,7,7a-hexahydro-6-hydroxy-7-Methyl-,Methyl ester, (1S,4aS,6S,7R,7aS) LOGANIN hplc Loganic glucopyranosyloxy)-1,4a,5,6,7,7a-hexahydro-6-hydroxy-7-methyl-,methyl ester, (1S,4aS,6S,7R,7aS) Loganin, >= Loganin (Loganoside) Loganin, 10 mM in DMSO Loganin, loganoside Cyclopenta[c]pyran-4-cboxylic acid, 1-(β-D-glucopyranosyloxy)-1,4a,5,6,7,7a-hexahydro-6-hydroxy-7-methyl-, methyl ester, (1S,4aS,6S,7R,7aS) (1S,4aS,6S,7R,7aS)-Methyl 6-hydroxy-7-methyl-1-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-cboxylate

Description	Loganin, a major iridoid glycoside obtained from Corni fructus, has been shown to have anti-inflammatory and anti-shock effects. Loganin exhibits an anti-inflammatory effect in cases of AP and its pulmonary complications through inhibition of NF-κB activation.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Others Natural Products >> Terpenoids and Glycosides
References	[1]. Kim MJ, et al. Loganin protects against pancreatitis by inhibiting NF-κB activation. Eur J Pharmacol. 2015 Oct 15;765:541-50. [2]. Tsai WH, et al. Ba-Wei-Di-Huang-Wan through its active ingredient loganin counteracts substance P-enhanced NF-κB/ICAM-1 signaling in rats with bladder hyperactivity. Neurourol Urodyn. 2015 Aug 19.

Density	1.5±0.1 g/cm3
Boiling Point	608.8±55.0 °C at 760 mmHg
Melting Point	222°C
Molecular Formula	C₁₇H₂₆O₁₀
Molecular Weight	390.382
Flash Point	217.9±25.0 °C
Exact Mass	390.152588
PSA	155.14000
LogP	-2.73
Vapour Pressure	0.0±4.0 mmHg at 25°C
Index of Refraction	1.600

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi
Risk Phrases	R22
Safety Phrases	S22-S45
RIDADR	1544
WGK Germany	3

Precursor 7
20586-11-2 139501-37-4 71462-04-9 186581-53-3
82509-41-9 80054-38-2 26660-57-1
DownStream 4
132237-63-9 132339-37-8 19351-63-4 99891-77-7

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