2682-20-4
2682-20-4 structure
- Name: 2-Methyl-4-Isothiazolin-3-one
- Chemical Name: methylisothiazolinone
- CAS Number: 2682-20-4
- Molecular Formula: C4H5NOS
- Molecular Weight: 115.154
- Catalog: analytical chemistry Standard Cosmetic standard
- Create Date: 2018-08-26 19:34:14
- Modify Date: 2026-06-30 17:54:44
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Methylisothiazolinone is a synthetic biocide and preservative that can be widely used in both industrial and consumer products. Methylisothiazolinone as a preservative in cosmetic and toiletrie products[1].
| Name | methylisothiazolinone |
|---|---|
| Synonyms |
N-METHYL-3-OXODIHYDRO ISOTHIAZOLE
2-METHYL-4-ISOTHIAZOLIN-3-ONE(MIT) WATER SOLUTION 2-METHYL-4-ISOTHIAZOLIN-3-ONE Methylisothiazolinone (2-Methyl-4-isothiazolin-3-one) 2-Methyl-3(2H)-isothiazolone 2-Methyl-2,3-dihydro-1,2-thiazol-3-one METHYLISOTHIAZOLINE MIT, 100ppm 2-methylisothiazolin-3-one MFCD00013254 2-Methyl-1,2-thiazol-3(2H)-one 2-methyl-1,2-thiazol-3-one KATHONCG MIT-10/2-methyl-4-ishothiazolin-3-one 2-Methylisothiazol-3-one 2- METHYL-4-ISOTHIAZOLINE-3-KETONE MIT-50/ Methylisothiazolinone N-Methylisothiazolone MI 2-methyl-3-isothiazolone Isothiazolone 5-chloro- Methyl-4-thiazoline-3-ketone(MI) Different thiazole moiety 1-(4-CHLOROPHENYL)-3-(3,4-DICHLOROPHENYL)UREA 2-Methyl-3-isothiazolone 2-Methyl-4-Isothiazolin-3-Ketone (MIT) 2-methyl-3(2h)-isothiazolon 2-METHYL-4-ISOTHIAZOLINE-3-ONE 2-Methyl-4-isothiazolin-3-on T5SNVJ B1 METHYLISOTHIAZOLONE 2-Methylisothiazolin-3-one 2-Methyl-4-isothiazolin (CMIT/MIT-14) 2-Methyl-4-Isothiazolin-3-one ( MIT ) / Isothiazolinones MIT 2-Methyl-4-isothiazoline-3-one 2-Methyl-4-isothiazolin-3-one, aqueous solution METHYLISOTHIAZOLIN 2-METHYLISOTHIAZOLINONE 2-Methyl-2,3-dihydroisothiazol-3-one 2-Methylisothiazole-3-one 2-METHYL-3(2H)-ISOTHIAZOLONE METHYLISOTHIAZDINONE Skycide 100 Methylisothiazolinone(MIT) methylisothiazolin-3-one 2-Methylisothiazol-3(2H)-one 2-Methyl-2H-isothiazole-3-one Isothiazolone,2-methyl 2-METHYLISOTHIAZOLIN-3(2H)-ONE 2-methyl-2H-isothiazol-3-one 3,4,4''-TRICHLOROCBANILIDE(TCC) Methyl isothiazalinone MIT-20 2-Methyl-4-Isothiazolin-3-Ketone Methyl-3(2H)-isothiazolone 2-Methyl-4-isothiazolin-3-one (Discontinued, see M314985) Methylisothiazolinone 2-methyl 4-isoisothiazolin-3-one 2-methylisothiazolone 2-METHYL-4-ISOTHIAZOLIN-3-ONE (MI) 3(2H)-Isothiazolone, 2-methyl EINECS 220-239-6 5-Chloro-2-methyl-4-isothiazolin-3-one/2-Methyl-4-isothiazolin (CMIT/MIT-14) N-methyl-isothiazole-HCl 2-Methyl-4-iso Skycide 2-Methyl-3-isothiazolone(MIT) 2-Methyl-4-isothiazolin-3-one,2-Methyl-3(2H)-isothiazolone 2-methyl-4-isothiazolin-3-one MIT |
| Description | Methylisothiazolinone is a synthetic biocide and preservative that can be widely used in both industrial and consumer products. Methylisothiazolinone as a preservative in cosmetic and toiletrie products[1]. |
|---|---|
| Related Catalog | |
| References |
[1]. Mari Paz Castanedo-Tardana, et al. Methylisothiazolinone. Dermatitis. Jan-Feb 2013;24(1):2-6. |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 182.8±23.0 °C at 760 mmHg |
| Melting Point | 254-256 °C(lit.) |
| Molecular Formula | C4H5NOS |
| Molecular Weight | 115.154 |
| Flash Point | 64.3±22.6 °C |
| Exact Mass | 115.009186 |
| PSA | 50.24000 |
| LogP | 0.05 |
| Vapour Pressure | 0.8±0.3 mmHg at 25°C |
| Index of Refraction | 1.589 |
CHEMICAL IDENTIFICATION
|
| Symbol |
GHS05, GHS06, GHS09 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H302-H314-H317-H331-H335-H400 |
| Precautionary Statements | P261-P273-P280-P305 + P351 + P338-P310 |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges |
| Hazard Codes | C:Corrosive |
| Risk Phrases | R20/21/22;R34;R43;R50 |
| Safety Phrases | S60-S61-S36/37/39-S26-S24-S45 |
| RIDADR | UN 3077 9/PG 3 |
| WGK Germany | 2 |
| RTECS | FE1250000 |
| Packaging Group | III |
| Hazard Class | 8 |
| HS Code | 2934100090 |
|
~56%
2682-20-4 |
| Literature: Clerici, Francesca; Contini, Alessandro; Gelmi, Maria Luisa; Pocar, Donato Tetrahedron, 2003 , vol. 59, # 47 p. 9399 - 9408 |
|
~99%
2682-20-4 |
| Literature: Tsolomitis, Athanase; Sandris, Constantine Heterocycles, 1987 , vol. 25, p. 569 - 575 |
|
~67%
2682-20-4 |
| Literature: Beeley, Nigel R. A.; Harwood, Laurence M.; Hedger, Paul C. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1994 , # 16 p. 2245 - 2252 |
|
~43%
2682-20-4 |
| Literature: Clerici, Francesca; Contini, Alessandro; Gelmi, Maria Luisa; Pocar, Donato Tetrahedron, 2003 , vol. 59, # 47 p. 9399 - 9408 |
|
~%
2682-20-4 |
| Literature: Lewis,S.N. et al. Journal of Heterocyclic Chemistry, 1971 , vol. 8, p. 571 - 580 |
|
~%
2682-20-4 |
| Literature: Easton, Christopher J. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 153 - 158 |
|
~%
2682-20-4 |
| Literature: Easton, Christopher J. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 153 - 158 |
| Precursor 4 | |
|---|---|
| DownStream 1 | |
| HS Code | 2934999090 |
|---|---|
| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |