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9003-39-8

9003-39-8 structure
9003-39-8 structure
  • Name: Polyvinylpyrrolidone
  • Chemical Name: poly(vinylpyrrolidone)
  • CAS Number: 9003-39-8
  • Molecular Formula: (C6H9NO)n
  • Molecular Weight: 111.1418 (monomer)
  • Catalog: API Blood system medication Blood volume expander
  • Create Date: 2018-02-08 08:00:00
  • Modify Date: 2024-01-02 20:43:49
  • Polyvinylpyrrolidone is a compound which has been widely tested and used in human and veterinary medicine as an effective wound healing accelerator and disinfectant when combined with iodine and other compounds.
Name poly(vinylpyrrolidone)
Synonyms k60
Polyvinylpyrrolidone
PVP
Kollidon K25
Kollidon K-90
k25
MFCD00149016
POP
Kollidon 25
k115
pvp2
pvp3
K-30
pvp4
PVPD
Description Polyvinylpyrrolidone is a compound which has been widely tested and used in human and veterinary medicine as an effective wound healing accelerator and disinfectant when combined with iodine and other compounds.
Related Catalog
In Vivo Goldfishes which are treated with salt have significantly lower mucus weights at 25 h. Goldfishes treated with Polyvinylpyrrolidone (PVP) have significantly higher mucus weights at 25 h. Koi treated with salt and Polyvinylpyrrolidone (PVP) has significantly lower mucus weight at 1 and 25 h. Control koi has significantly higher mucus at 25 h. At the end of 2 weeks, it is determined that the three koi treated with salt and Polyvinylpyrrolidone(PVP) remain healthy and show a higher degree of healing than other treatment koi and the control group[1].
Animal Admin Each fish within a tank serves as a replicate. Treatments are designated as Polyvinylpyrrolidone (at a dose of 10 mL/10 gallon) and saline/salt at 3g/L. A control group that does not receive any chemical is also included in the study. All fishes from each treatment group are sampled at 0 min, 15 min, 1 h, 4 h and 25 h. At each time interval, all fishes from each treatment group are anaesthetized using buffered tricaine methanesulfonate, weighed, and slime is scraped from one 1 cm2 area over the epaxial musculature using a preweighed plastic coverslip[1].
References

[1]. Shivappa RB, et al. Laboratory evaluation of different formulations of Stress Coat? for slime production in goldfish (Carassius auratus) and koi (Cyprinus carpio). PeerJ. 2017 Sep 6;5:e3759.

Density 1.144g/cm3
Boiling Point 217.6ºC at 760 mmHg
Melting Point 130ºC
Molecular Formula (C6H9NO)n
Molecular Weight 111.1418 (monomer)
Flash Point 93.9ºC
PSA 20.31000
LogP 0.69020
Storage condition Store at RT.
Water Solubility H2O: soluble100mg/mL

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TR8300000
CHEMICAL NAME :
Poly(1-vinyl-2-pyrrolidinone) Hueper's Polymer No.5
CAS REGISTRY NUMBER :
9003-39-8
LAST UPDATED :
199710
DATA ITEMS CITED :
9
WISWESSER LINE NOTATION :
/T5NVTJ AY*1*/

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2500 mg/kg
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors Endocrine - tumors
REFERENCE :
AMPLAO AMA Archives of Pathology. (Chicago, IL) V.50(4)-69, 1950-60. For publisher information, see APLMAS. Volume(issue)/page/year: 67,589,1959
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2500 mg/kg
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors Reproductive - Tumorigenic effects - uterine tumors
REFERENCE :
AMPLAO AMA Archives of Pathology. (Chicago, IL) V.50(4)-69, 1950-60. For publisher information, see APLMAS. Volume(issue)/page/year: 67,589,1959
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
8000 mg/kg
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Cardiac - tumors Endocrine - tumors
REFERENCE :
AMPLAO AMA Archives of Pathology. (Chicago, IL) V.50(4)-69, 1950-60. For publisher information, see APLMAS. Volume(issue)/page/year: 67,589,1959 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 19,461,1979 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81235 No. of Facilities: 7856 (estimated) No. of Industries: 50 No. of Occupations: 63 No. of Employees: 102100 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7211 No. of Facilities: 7688 (estimated) No. of Industries: 46 No. of Occupations: 63 No. of Employees: 161259 (estimated) No. of Female Employees: 84819 (estimated)
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xn
Safety Phrases S24/25
RIDADR NONH for all modes of transport
WGK Germany 1
RTECS TR8370000
HS Code 3905990000
88-12-0 structure

88-12-0

~%

9003-39-8 structure

9003-39-8

Literature: US2006/216263 A1, ; Page/Page column 5-6 ;
Precursor  1

DownStream  0

HS Code 3905990000

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