2310-17-0

2310-17-0 structure

Name: Phosalone
Chemical Name: phosalone
CAS Number: 2310-17-0
Molecular Formula: C₁₂H₁₅ClNO₄PS₂
Molecular Weight: 367.809
Catalog: Chemical pesticide Insecticide Organophosphorus pesticide
Create Date: 2018-05-11 08:00:00
Modify Date: 2026-07-01 00:07:13
Phosalone is a member of the organophosphate family of insecticides. It is used as both an insecticide and acaricide.

Name	phosalone
Synonyms	6-chloro-2,3-dihydro-2-oxobenzoxazol-3-ylmethyl O,O-diethyl phosphorodithioate o,o-diethyl-s-(6-chlorobenzoxazonyl-3-methyl)dithiophosphate benzphos niaga9241 o,o-diaethyl-s-(6-chlor-2-oxo-ben(b)-1,3-oxalin-3-yl)-methyl-dithiophosphat(ge aia1060 EINECS 218-996-2 bensophos s-6-chloro-2,3-dihydro-2-oxo-1,3-benzoxazol-3-ylmethylo,o-diethylphosphorodit S-[(6-Chlor-2-oxo-1,3-benzoxazol-3(2H)-yl)methyl]-O,O-diethyldithiophosphat Phosphorodithioic Acid S-[(6-Chloro-2-oxo-3(2H)-benzoxazolyl)methyl] O,O-Diethyl Ester MFCD00055499 nzoxazolinone Zolone PM Embacide S-6-chloro-2,3-dihydro-2-oxo-1,3-benzoxazol-3-ylmethyl O,O-diethyl phosphorodithioate 3-(o,o-diethyldithiophosphorylmethyl)-6-chlorobenzoxazolinone o,o-diethylphosphorodithioate,s-esterwith6-chloro-3-(mercaptomethyl)-2-benz zolon 11974rp o,o-diethyl-s-((6-chloor-2-oxo-benzoxazolin-3-yl)-methyl)-dithiofosfaat S-[(6-chloro-2-oxo-3(2H)-benzoxazolyl)methyl] O,O-diethyl phosphorodithioate benzophosphate 6-chloro-3-(o,o-diethyldithiophosphorylmethyl)benzoxazolone o,o-dietil-s-((6-cloro-2-oxo-benzossazolin-3-il)-metil)-ditiofosfato S-6-Chloro-2,3-dihydro-2-oxobenzoxazol-3-ylmethyl phosphorodithioate oxazolinone chipman11974 o,o-diethylphosphorodithioate,s-esterwith6-chloro-3-(mercaptomethyl)-2-be Phasolon fosalon ent27 Zoolon Fozalon Phosphorodithioic Acid O,O-Diethyl Ester S-Ester with 6-Chloro-3-(mercaptomethyl)-2-benzoxazolinone RUBITOX Ribitox Benzophosphate ZOLONE 3-(o,o-diethyldithiophosphorylmethyl)-6-chlorobenzoxazolone o,o-diaethyl-s-(6-chlor-2-oxo-ben(b)-1,3-oxalin-3-yl)-methyl-dithiophosphat zolonedt o,o-diaethyl-s-(6-chlor-benzoxazolon-2-on-3-yl)-dithiophosphat 6-chloro-3-diethoxyphosphinothioylthiomethyl-1,3-benzoxazol-2(3h)-one p-974 zolonm o,o-diethyl-s-(6-chloro-2-oxo-benzoxazolin-3-yl)methyl-phosphorothiolothionate Phosphorodithioic acid, S-[(6-chloro-2-oxo-3(2H)-benzoxazolyl)methyl] O,O-diethyl ester O,O-Diethyl phosphorodithioate S-ester with 6-chloro-3-(mercaptomethyl)-2-benzoxazolinone S-6-chloro-2,3-dihydro-2-oxobenzoxazol-3-ylmethylO,O-diethylphosphorodithioate 3-(6-chloro-2-oxobenzoxazolin-3-yl)methylo,o-diethylphosphorothiolothionate 3-diethyldithiophosphorylmethyl-6-chlorobenzoxazolone-2 nia9241 s-6-chloro-2,3-dihydro-2-oxobenzoxazol-3-ylmethylo,o-diethylphosphorodithioat Chipman Fosalone 3-[O,O-(Diethyldithiophosphoryl)methyl]-6-chlorobenzoxazolinone 6-Chloro-3-[O,O-(diethyldithiophosphoryl)methyl]benzoxazolone benzofos S-6-chloro-2,3-dihydro-2-oxobenzoxazol-3-ylmethyl O,O-diethyl phosphorodithioate 11974 RP o,o-diethyl-s-(6-chloro-2-oxo-benzoxazolin-3-yl)methyl-phosphorothiolothiona Dithiophosphate de S-[(6-chloro-2-oxo-1,3-benzoxazol-3(2H)-yl)méthyle] et de O,O-diéthyle o,o-diethyls-(6-chlorobenzoxazolinyl-3-methyl)dithiophosphate AZOFENE hyl)-2-benzoxazolinone 3-(6-chloro-2-oxobenzoxazolin-3-yl)methyl-o,o-diethylphosphorothiolothionate nia-9241 nph-1091 S-[(6-Chloro-2-oxo-1,3-benzoxazol-3(2H)-yl)methyl] O,O-diethyl phosphorodithioate Zolon

Description	Phosalone is a member of the organophosphate family of insecticides. It is used as both an insecticide and acaricide.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Infection

Density	1.4±0.1 g/cm3
Boiling Point	446.7±55.0 °C at 760 mmHg
Melting Point	45-48ºC
Molecular Formula	C₁₂H₁₅ClNO₄PS₂
Molecular Weight	367.809
Flash Point	223.9±31.5 °C
Exact Mass	366.986847
PSA	120.80000
LogP	4.28
Vapour Pressure	0.0±1.1 mmHg at 25°C
Index of Refraction	1.609

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TD5175000

CHEMICAL NAME :: Phosphorodithioic acid, S-((6-chloro-2-oxo-3(2H)-benzoxazolyl)methyl) O,O-diethyl ester

CAS REGISTRY NUMBER :: 2310-17-0

LAST UPDATED :: 199806

DATA ITEMS CITED :: 19

MOLECULAR FORMULA :: C12-H15-Cl-N-O4-P-S2

MOLECULAR WEIGHT :: 367.82

WISWESSER LINE NOTATION :: T56 BNVOJ B1SPS&O2&O2 GG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 85 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: KSKZAN Khimiya v Sel'skom Khozyaistve. Chemistry in Agriculture. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) No.1- 1963- Volume(issue)/page/year: 16(2),59,1978

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 390 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: WRPCA2 World Review of Pest Control. (London, UK) V.1-10, 1962-71. Discontinued. Volume(issue)/page/year: 9,119,1970

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 135 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 30ZDA9 "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971 Volume(issue)/page/year: -,371,1971

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 73 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 19(9),55,1975

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - cat

DOSE/DURATION :: 112 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 14(12),46,1970

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85DPAN "Wirksubstanzen der Pflanzenschutz und Schadlingsbekampfungsmittel," Perkow, W., Berlin, Verlag Paul Parey, 1971-1976 Volume(issue)/page/year: -,-,1971/1976

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 150 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GUCHAZ Guide to the Chemicals Used in Crop Protection. (Information Canada, 171 Slater St., Ottawa, Ont., Canada) Volume(issue)/page/year: 6,408,1973

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - chicken

DOSE/DURATION :: 661 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: VETNAL Veterinariya. Veterinary Science. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1924- Volume(issue)/page/year: 54(11),75,1978

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: 400 mg/kg

TOXIC EFFECTS :: Blood - other changes Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases

REFERENCE :: IJTHEZ International Journal of Toxicology, Occupational and Environmental Health. (Wiley Eastern, 4835/24 Ansari Road, Daryaganj New Delhi 110002, India) V.1- 1991- Volume(issue)/page/year: 1,186,1991 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 803 mg/kg/17W-I

TOXIC EFFECTS :: Liver - hepatitis (hepatocellular necrosis), zonal Liver - other changes Vascular - structural changes in vessels

REFERENCE :: EKMMA8 Eksperimentalna Meditsina i Morfologiya. (Hemus, Blvd. Russki 6, Sofia, Bulgaria) V.1- 1962- Volume(issue)/page/year: 18,177,1979

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 262 mg/kg/3W-I

TOXIC EFFECTS :: Liver - other changes Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases

REFERENCE :: ENVRAL Environmental Research. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1967- Volume(issue)/page/year: 44,126,1987

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 524 mg/kg/26W-I

TOXIC EFFECTS :: Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - catalases

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 50(2),73,1985

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 8925 mg/kg/2Y-C

TOXIC EFFECTS :: Brain and Coverings - other degenerative changes Blood - other changes Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 36,561,1976

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 515 ug/kg/24H/92D-C

TOXIC EFFECTS :: Kidney, Ureter, Bladder - other changes in urine composition Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 41(7),10,1976

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 3640 mg/kg/2Y-C

TOXIC EFFECTS :: Blood - other changes Nutritional and Gross Metabolic - weight loss or decreased weight gain Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 36,561,1976 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 264 mg/kg

SEX/DURATION :: female 1-22 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Newborn - biochemical and metabolic

REFERENCE :: PRKHDK Problemi na Khigienata. Problems in Hygiene. (Durzhavno Izdatel'stvo Meditsina i Fizkultura, Pl. Slaveikov 11, Sofia, Bulgaria) V.1- 1975- Volume(issue)/page/year: 2,169,1976 *** REVIEWS *** TOXICOLOGY REVIEW RREVAH Residue Reviews. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1962- Volume(issue)/page/year: 63,1,1976 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989

Symbol	GHS06, GHS09
Signal Word	Danger
Hazard Statements	H301 + H311-H317-H332-H410
Precautionary Statements	P261-P273-P280-P301 + P310 + P330-P302 + P352 + P312-P304 + P340 + P312
Personal Protective Equipment	Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes	T,N
Risk Phrases	R21
Safety Phrases	S36/37-S45-S60-S61
RIDADR	2783
RTECS	TD5175000
Packaging Group	III
Hazard Class	6.1(b)
HS Code	2934999021

50-00-0

19932-84-4

298-06-6

2310-17-0

Literature: Helvetica Chimica Acta, , vol. 57, p. 1658 - 1675

Precursor 3
50-00-0 19932-84-4 298-06-6
DownStream 0

HS Code	2934999021
Summary	2934999021 o,o-dimethyl s-(2-morpholino-2-oxoethyl) phosphorodithioate。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:20.0%

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