93129-94-3

93129-94-3 structure

Name: Tacalcitol monohydrate
Chemical Name: 1,3-Cyclohexanediol, 4-methylene-5-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R,4R)-4-hydroxy-1,5-dimethylhexyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-, hydrate , (1R,3S,5Z)
CAS Number: 93129-94-3
Molecular Formula: C₂₇H₄₆O₄
Molecular Weight: 434.652
Catalog: Signaling Pathways Vitamin D Related VD/VDR
Create Date: 2018-02-11 08:00:00
Modify Date: 2026-07-03 13:00:09
Tacalcitol monohydrate (1,24(R)-Dihydroxyvitamin D3; 1.alpha.,24R-Dihydroxyvitamin D3) promotes normal bone development by regulating calcium.IC50 value:Target: Tacalcitol modulates immunological and inflammatory processes. Tacalcitol induces nerve growth factor production in epidermal keratinocytes.

Name	1,3-Cyclohexanediol, 4-methylene-5-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R,4R)-4-hydroxy-1,5-dimethylhexyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-, hydrate , (1R,3S,5Z)
Synonyms	(1R,3S)-5-[2-[(1R,3,7aS)-1-[(2R,5S)-5-hydroxy-6-methyl-htan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexane-1,3-diol 1,24(R)-DihydroxyvitaMin D3, Monohydrate 1α,24(R)-Dihydroxycholecalciferol monohydrate 1,3-Cyclohexanediol, 4-methylene-5-[(2E)-2-[(1R,3aS,7-octahydro-1-[(1R,4R)-4-hydroxy-1,5-dimethylhexyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-, hydrate , (1R,3S,5Z) CB91456900 Tacalcitol (monohydrate) (1R,3S)-5-[2-[(1R,3AR,7AS)-1-[(2R,5S)-5-HYDROXY-6-METHYL-HEPTAN-2-YL]-7A-METHYL-2,3,3A,5,6,7-HEXAHYD 9,10-Secocholesta-5,7,10-triene-1,3,24-triol,Monohydrate, (1a,3b,5Z,7E,24R)- (9CI) (1R,3S)-5-[2-[(1R,3,7aS)-1-[(2R,5S)-5-hydroxy-6-Methyl-htan-2-yl]-7a-Methyl-2,3,3a,5,6,7-hexahyd 1,3-Cyclohexanediol, 4-methylene-5-[(2E)-2-[(1R,3aS,7-octahydro-1-[(1R,4R)-4-hydroxy-1,5-dimethylhexyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-, hydrate (1:1), (1R,3S,5Z) 1α,24(R)-Dihydroxy-vitamin D3 monohydrate (1R,3S,Z)-5-(2-((1R,3aS,7,E)-1-((2R,5R)-5-Hydroxy-6-methylhtan-2-yl)-7a-methyloctahydro-4H-inden-4-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol hydrate 24(R)-Dihydroxyvitamin D3 monohydrate (1S,3R,5Z,7E,24R)-9,10-Secocholesta-5,7,10-triene-1,3,24-triol hydrate (1:1) 1,3-Cyclohexanediol, 4-methylene-5-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R,4R)-4-hydroxy-1,5-dimethylhexyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-, (1R,3S,5Z)-, hydrate (1:1) 1,24-dihydroxy Vitamin D3 (hydrate) 1-alpha,24(R)-Dihydroxyvitamin D3 monohydrate Curatoderm monohydrate\|\|\|TV 02 monohydrate\|\|\|TV-02H monohydrate\|\|\|1,24(R)-Dihydroxyvitamin D3 monohydrate 24(R)-Dihydroxyvitamin D3

Description	Tacalcitol monohydrate (1,24(R)-Dihydroxyvitamin D3; 1.alpha.,24R-Dihydroxyvitamin D3) promotes normal bone development by regulating calcium.IC50 value:Target: Tacalcitol modulates immunological and inflammatory processes. Tacalcitol induces nerve growth factor production in epidermal keratinocytes.
Related Catalog	Signaling Pathways >> Vitamin D Related >> VD/VDR Research Areas >> Others
References	[1]. Koyano K, Saitoh Y, Oshida J, Takimoto-Kamimura M.Dimer and superstructure of the active form of a vitamin D3; 1 alpha,24(R)dihydroxy-vitamin D3 monohydrate, C27O3H44.H2O.Chem Pharm Bull (Tokyo). 2001 Mar;49(3):305-11. [2]. Fukuoka et alTacalcitol, an active vitamin D3, induces nerve growth factor in human epidermal keratinocytes. Skin Pharmacol.Appl.Skin Physiol. (2001) 14 226. [3]. Rostowska-Nadolska et al Vitamin D derivatives: calcitriol and tacalcitol inhibits interleukin-6 and interleukin-8 expression in human nasal polyp fibroblasts. Adv.Med.Sci. (2010) 55 86.

Molecular Formula	C₂₇H₄₆O₄
Molecular Weight	434.652
Exact Mass	434.339600
PSA	69.92000
LogP	5.49630
Storage condition	2-8℃

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