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226700-79-4

226700-79-4 structure
226700-79-4 structure
  • Name: fosamprenavir
  • Chemical Name: fosamprenavir
  • CAS Number: 226700-79-4
  • Molecular Formula: C25H36N3O9PS
  • Molecular Weight: 585.61
  • Catalog: Signaling Pathways Anti-infection HIV
  • Create Date: 2018-02-12 08:00:00
  • Modify Date: 2024-01-05 00:15:58
  • Fosamprenavir (Amprenavir phosphate;GW 433908) is a phosphate ester prodrug of the antiretroviral protease inhibitor Amprenavir, with improved solubility[1]. Anti-HIV infection[1].

Name fosamprenavir
Synonyms fosamprenavir
(3S)-Tetrahydro-3-furanyl [(2S,3R)-4-{[(4-aminophenyl)sulfonyl](isobutyl)amino}-1-phenyl-3-(phosphonooxy)-2-butanyl]carbamate
Lexiva
Amprenavir phosphate
((1S,2R)-3-(((4-Aminophenyl)sulfonyl)(2-methylpropyl)amino)-1-(phenylmethyl)-2-(phosphonooxy)propyl)carbamic Acid C-((3S)-Tetrahydro-3-furanyl) Ester
((3S)Oxolan-3-yloxy)-N-((1S,2R)-3-{[(4-aminophenyl)sulfonyl](2-methylpropyl)amino}-1-benzyl-2-(phosphonooxy)propyl)carboxamide
(3S)-Tetrahydrofuran-3-yl [(2S,3R)-4-{[(4-aminophenyl)sulfonyl](isobutyl)amino}-1-phenyl-3-(phosphonooxy)butan-2-yl]carbamate
GW 433 908
Carbamic acid, N-[(1S,2R)-3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-1-(phenylmethyl)-2-(phosphonooxy)propyl]-, (3S)-tetrahydro-3-furanyl ester
Description Fosamprenavir (Amprenavir phosphate;GW 433908) is a phosphate ester prodrug of the antiretroviral protease inhibitor Amprenavir, with improved solubility[1]. Anti-HIV infection[1].
Related Catalog
Target

HIV[1]

References

[1]. Falcoz C, et al. Pharmacokinetics of GW433908, a prodrug of amprenavir, in healthy male volunteers. J Clin Pharmacol. 2002 Aug;42(8):887-98.

Density 1.4±0.1 g/cm3
Molecular Formula C25H36N3O9PS
Molecular Weight 585.61
Exact Mass 585.190979
PSA 195.91000
LogP 3.36
Index of Refraction 1.612
Storage condition 2-8℃