5943-61-3

5943-61-3 structure
5943-61-3 structure
  • Name: Tetraethyl octane-1,8-diylbis(phosphonate)
  • Chemical Name: Octamethylen-bis-(diethylphosphonat)
  • CAS Number: 5943-61-3
  • Molecular Formula: C16H36O6P2
  • Molecular Weight: 386.40100
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2017-03-20 11:06:16
  • Modify Date: 2024-01-31 17:41:05
  • Tetraethyl octane-1,8-diylbis(phosphonate) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Octamethylen-bis-(diethylphosphonat)
Synonyms MFCD24539459
Description Tetraethyl octane-1,8-diylbis(phosphonate) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl-Chain

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C16H36O6P2
Molecular Weight 386.40100
Exact Mass 386.19900
PSA 90.68000
LogP 5.85920
Precursor  0

DownStream  1