Tetraethyl octane-1,8-diylbis(phosphonate)

Modify Date: 2025-09-12 04:14:27

Tetraethyl octane-1,8-diylbis(phosphonate) Structure
Tetraethyl octane-1,8-diylbis(phosphonate) structure
Common Name Tetraethyl octane-1,8-diylbis(phosphonate)
CAS Number 5943-61-3 Molecular Weight 386.40100
Density N/A Boiling Point N/A
Molecular Formula C16H36O6P2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Tetraethyl octane-1,8-diylbis(phosphonate)


Tetraethyl octane-1,8-diylbis(phosphonate) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Octamethylen-bis-(diethylphosphonat)
Synonym More Synonyms

  Biological Activity

Description Tetraethyl octane-1,8-diylbis(phosphonate) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl-Chain

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C16H36O6P2
Molecular Weight 386.40100
Exact Mass 386.19900
PSA 90.68000
LogP 5.85920

 Precursor & DownStream

Precursor  0

DownStream  1

 Synonyms

MFCD24539459
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