Top Suppliers:I want be here

7236-57-9

7236-57-9 structure
7236-57-9 structure
  • Name: 4-thiothymidine
  • Chemical Name: Thymidine, 4-thio
  • CAS Number: 7236-57-9
  • Molecular Formula: C10H14N2O4S
  • Molecular Weight: 258.29
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
  • Create Date: 2018-07-18 12:04:09
  • Modify Date: 2024-01-11 23:29:38
  • 4-Thiothymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name Thymidine, 4-thio
Synonyms deoxy-4-thiothymidine
4-thio-thymidine
4-Thio-thymidin
2(1H)-Pyrimidinone, 1-(2-deoxy-β-D-erythro-pentofuranosyl)-3,4-dihydro-5-methyl-4-thioxo-
4-thiothymidine
1-(2-Deoxy-β-D-erythro-pentofuranosyl)-5-methyl-4-thioxo-3,4-dihydro-2(1H)-pyrimidinone
Description 4-Thiothymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Density 1.5±0.1 g/cm3
Molecular Formula C10H14N2O4S
Molecular Weight 258.29
Exact Mass 258.067413
PSA 119.57000
LogP -0.07
Index of Refraction 1.672
Hazard Codes Xi