86933-74-6

86933-74-6 structure
86933-74-6 structure

Name neurokinin a
Synonyms NEUROKININ A (PORCINE)
Neurokinin A,α-Neurokinin,Neuromedin L,Substance K
H-HIS-LYS-THR-ASP-SER-PHE-VAL-GLY-LEU-MET-NH2
Neurokinin A: Substance K: Neuromedin L: NKA
MFCD00167560
SUBSTANCE K (HUMAN, PORCINE, RAT, MOUSE)
NEUROMEDIN L
A-neurokinin
NEUROKININ A (HUMAN, PORCINE, RAT, MOUSE)
NEUROKININ A
Neurokinin A, Tachykinin ptide
Neurokinin A NKA, Substance K, Neurokinin α, NeuroMedin L
TAC2
L-His-L-Lys-L-Thr-L-Asp-L-Ser-L-Phe-L-Val-Gly-L-Leu-L-Met-NH2
NEUROKININ A //BP
ALPHA-NEUROKININ
α-neurokinin
NEUROKININ ALPHA
Neurokinin A [NKA]
L-Methioninamide, L-histidyl-L-lysyl-L-threonyl-L-α-asptyl-L-seryl-L-phenylalanyl-L-valylglycyl-L-leucyl
HIS-LYS-THR-ASP-SER-PHE-VAL-GLY-LEU-MET-NH2
α-Neurokinin, Neuromedin L, Substance K
NKA, Substance K, Neurokinin a, NeuroMedin L
SUBSTANCE K
HKTDSFVGLM-NH2
Inhibitor,Neurokinin Rector,Neurokinin α,Tachykinin rector,inhibit,Neurokinin A,NK rector
NEUROMEDIN L (HUMAN, PORCINE, RAT, MOUSE)
TKN1
Description Neurokinin A acts via neurokinin 2 (NK-2) receptor.
Related Catalog
Target

NK-2 receptor[1]

In Vitro Neurokinin A (substance K) is a peptide neurotransmitter of the tachykinin family with potential as a major mediator in human airway and gastrointestinal tissues. Neurokinin A acts via the NK-2 receptor believed to be localized on smooth muscle cells and pharmacologically coupled to a GTP-binding protein. Neurokinin A is a member of a family of peptide neurotransmitters known as tachykinins. These peptides are associated with the central and peripheral nervous systems and display a wide tissue distribution. Tachykinins share the COOH-terminal structure Phe-X-Gly-Leu-Met-NH. The best known members of this family are Substance P and Neurokinin A or Substance K[1].
References

[1]. Gerard NP, et al. The human neurokinin A (substance K) receptor. Molecular cloning of the gene, chromosome localization, and isolation of cDNA from tracheal and gastric tissues. J Biol Chem. 1990 Nov 25;265(33):20455-62.

Density 1.305 g/cm3
Boiling Point 1610.7ºC at 760 mmHg
Molecular Formula C50H80N14O14S
Molecular Weight 1133.32000
Flash Point 927.9ºC
Exact Mass 1132.57000
PSA 488.77000
LogP 1.05310
Index of Refraction 1.58
Storage condition -20°C
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Risk Phrases R20/21/22
Safety Phrases S36
RIDADR NONH for all modes of transport
WGK Germany 3
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