Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 4(1H)-Pyrimidinone,2,3-dihydro-5,6-dimethyl-2-thioxo-
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

28456-54-4

28456-54-4 structure

Name: 5,6-dimethyl-2-Thiouracil
Chemical Name: 5,6-Dimethyl-2-thiouracil
CAS Number: 28456-54-4
Molecular Formula: C₆H₈N₂OS
Molecular Weight: 156.20600
Catalog: Pharmaceutical intermediate Heterocyclic compound Pyrimidine compound Urinary (urea)pyrimidine
Create Date: 2018-04-12 08:00:00
Modify Date: 2024-01-16 12:43:31

Name	5,6-Dimethyl-2-thiouracil
Synonyms	5,6-dimethyl-2-sulfanylidene-1H-pyrimidin-4-one MFCD00278872

Density	1.29g/cm3
Boiling Point	347.3ºC at 760mmHg
Melting Point	284-288ºC(lit.)
Molecular Formula	C₆H₈N₂OS
Molecular Weight	156.20600
Flash Point	163.9ºC
Exact Mass	156.03600
PSA	84.81000
LogP	1.08770
Vapour Pressure	2.7E-05mmHg at 25°C
Index of Refraction	1.61

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YQ9887000

CHEMICAL NAME :: Uracil, 5,6-dimethyl-2-thio-

CAS REGISTRY NUMBER :: 28456-54-4

BEILSTEIN REFERENCE NO. :: 0118811

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C6-H8-N2-O-S

MOLECULAR WEIGHT :: 156.22

WISWESSER LINE NOTATION :: T6MYMVJ BUS E1 F1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 250 mg/kg

TOXIC EFFECTS :: Behavioral - antipsychotic

REFERENCE :: CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA, 1255 Howard St., San Francisco, CA 94103) V.6- 1958- Volume(issue)/page/year: 6,490,1958

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi: Irritant;
Risk Phrases	36/37/38
Safety Phrases	26-36
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	YQ9887000
HS Code	2933599090

609-14-3

17356-08-0

~77%

28456-54-4

Literature: ABBVIE INC.; DEKHTYAR, Tatyana; GOMTSYAN, Arthur; MOLLA, M-Akhteruzzaman; VASUDEVAN, Anil; NG, Teresa (Iok Chan); SHAFEEV, Mikhail Patent: WO2013/123401 A1, 2013 ; Location in patent: Page/Page column 39 ;

17094-21-2

17356-08-0

28456-54-4

Literature: Roth, Joshua; Minond, Dmitriy; Darout, Etzer; Liu, Qin; Lauer, Janelle; Hodder, Peter; Fields, Gregg B.; Roush, William R. Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 23 p. 7180 - 7184

Precursor 2
609-14-3 17094-21-2
DownStream 5
67434-65-5 31408-09-0 34916-78-4 26305-13-5
1780-32-1

HS Code	2933599090
Summary	2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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