28456-54-4
28456-54-4 structure
- Name: 5,6-dimethyl-2-Thiouracil
- Chemical Name: 5,6-Dimethyl-2-thiouracil
- CAS Number: 28456-54-4
- Molecular Formula: C6H8N2OS
- Molecular Weight: 156.20600
- Catalog: Pharmaceutical intermediate Heterocyclic compound Pyrimidine compound Urinary (urea)pyrimidine
- Create Date: 2018-04-12 08:00:00
- Modify Date: 2026-07-08 16:45:02
| Name | 5,6-Dimethyl-2-thiouracil |
|---|---|
| Synonyms |
4-pyrimidinol, 2-mercapto-5,6-dimethyl
5,6-Dimethyl-2-sulphanylpyrimidin-4-ol, 5,6-Dimethyl-4-hydroxy-2-mercapto-1,3-diazine 5,6-Dimethyl-4-hydroxy-2-thiopyrimidine 5,6-dimethyl-2-thioxo-1H-pyrimidin-4-one 4(1H)-Pyrimidinone, 2,3-dihydro-5,6-dimethyl-2-thioxo 5,6-Dimethyl-2-thioxo-2,3-dihydropyrimidin-4(1H) 2-Mercapto-5,6-dimethylpyrimidin-4(3H)-one MFCD00278872 2-mercapto-5,6-dimethylpyrimidin-4-ol 5,6-dimethyl-2-sulfururacil Uracil, 5,6-dimethyl-2-thio 5,6-dimethyl-2-sulfanylidene-1H-pyrimidin-4-one 5,6-dimethyl-2-thio-uraci 5,6-Dimethyl-2(1H)-thioxopyrimidine-4(3H)-one 5,6-diMethyl-2-sulfanylpyriMidin-4-ol 2-Mercapto-5,6-dimethylpyrimidine-4-ol 5,6-DIMETHYL-2-THIOURACIL 5,6-Dimethylthiouracil Brn Nsc |
| Density | 1.29g/cm3 |
|---|---|
| Boiling Point | 347.3ºC at 760mmHg |
| Melting Point | 284-288ºC(lit.) |
| Molecular Formula | C6H8N2OS |
| Molecular Weight | 156.20600 |
| Flash Point | 163.9ºC |
| Exact Mass | 156.03600 |
| PSA | 84.81000 |
| LogP | 1.08770 |
| Vapour Pressure | 2.7E-05mmHg at 25°C |
| Index of Refraction | 1.61 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
|
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | 36/37/38 |
| Safety Phrases | 26-36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | YQ9887000 |
| HS Code | 2933599090 |
|
~77%
28456-54-4 |
| Literature: ABBVIE INC.; DEKHTYAR, Tatyana; GOMTSYAN, Arthur; MOLLA, M-Akhteruzzaman; VASUDEVAN, Anil; NG, Teresa (Iok Chan); SHAFEEV, Mikhail Patent: WO2013/123401 A1, 2013 ; Location in patent: Page/Page column 39 ; |
|
~%
28456-54-4 |
| Literature: Roth, Joshua; Minond, Dmitriy; Darout, Etzer; Liu, Qin; Lauer, Janelle; Hodder, Peter; Fields, Gregg B.; Roush, William R. Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 23 p. 7180 - 7184 |
| Precursor 2 | |
|---|---|
| DownStream 5 | |
| HS Code | 2933599090 |
|---|---|
| Summary | 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |