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102-37-4

102-37-4 structure
102-37-4 structure
  • Name: Ethyl 3-(3,4-dihydroxyphenyl)acrylate
  • Chemical Name: Ethyl 3-(3,4-dihydroxyphenyl)acrylate
  • CAS Number: 102-37-4
  • Molecular Formula: C11H12O4
  • Molecular Weight: 208.211
  • Catalog: Signaling Pathways Immunology/Inflammation COX
  • Create Date: 2018-03-14 08:00:00
  • Modify Date: 2024-01-02 18:08:41
  • Ethyl Caffeate is a natural phenolic compound isolated from Bidens pilosa. Ethyl caffeate suppresses NF-κB activation and its downstream inflammatory mediators, inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), and prostaglandin E2 (PGE2) in vitro or in mouse skin[1].

Name Ethyl 3-(3,4-dihydroxyphenyl)acrylate
Synonyms Ethyl (2E)-3-(3,4-dihydroxyphenyl)acrylate
Ethyl caffeate
MFCD00045754
caffeic acid ethyl ester
(E)-ethyl 3-(3,4-dihydroxyphenyl)acrylate
3,4-Dihydroxycinnamic acid ethyl ester
ethyl (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
2-Propenoic acid, 3-(3,4-dihydroxyphenyl)-, ethyl ester
ETHYL TRANS-CAFFEATE
ETHYL 3,4-DIHYDROXYCINNAMATE
2-Propenoic acid, 3-(3,4-dihydroxyphenyl)-, ethyl ester, (2E)-
Description Ethyl Caffeate is a natural phenolic compound isolated from Bidens pilosa. Ethyl caffeate suppresses NF-κB activation and its downstream inflammatory mediators, inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), and prostaglandin E2 (PGE2) in vitro or in mouse skin[1].
Related Catalog
Target

NF-κB

COX-2

In Vitro Ethyl Caffeate markedly suppresses the lipopolysaccharide (LPS)-induced nitric oxide (NO) production with IC50 of 5.5 μg/ml[1].
References

[1]. Chiang YM, et al. Ethyl caffeate suppresses NF-kappaB activation and its downstream inflammatory mediators, iNOS, COX-2, and PGE2 in vitro or in mouse skin. Br J Pharmacol. 2005 Oct;146(3):352-63.

Density 1.3±0.1 g/cm3
Boiling Point 377.0±32.0 °C at 760 mmHg
Molecular Formula C11H12O4
Molecular Weight 208.211
Flash Point 148.4±18.6 °C
Exact Mass 208.073563
PSA 66.76000
LogP 1.72
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.612
Storage condition 2-8°C
Hazard Codes Xi
HS Code 2918290000
HS Code 2918290000
Summary HS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0%