61090-95-7

61090-95-7 structure

Name: H-Tyr-D-Ala-Gly-Phe-Met-NH2
Chemical Name: 2-[[2-[[2-[2-[[2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoylamino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylsulfanylbutanamide
CAS Number: 61090-95-7
Molecular Formula: C₂₈H₃₈N₆O₆S
Molecular Weight: 586.70300
Catalog: Signaling Pathways GPCR/G Protein Opioid Receptor
Create Date: 2016-02-11 22:56:58
Modify Date: 2024-01-08 14:43:04
[D-Ala2]-Met-Enkephalinamide, an opioid peptide, is a potent opioid agonist. [D-Ala2]-Met-Enkephalinamide decreases bile flow by a central mechanism. [D-Ala2]-Met-Enkephalinamide has analgesic properties[1][2].

Name	2-[[2-[[2-[2-[[2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoylamino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylsulfanylbutanamide
Synonyms	DAME [D-Ala2]Met-enkephalinamide D-Enkephalin Met-enkephalinamide,ala(2) [D-Ala2-Met5]enkephalinamide Methionine-enkephalinamide,ala(2) Enkephalinamide-met,ala(2) Tyr-D-Ala-Gly-Phe-Met-NH2 Dalamid Dalamide 2-Ala-met-enkephalinamide Enkephalinamide-met,alanine(2) [D-Ala2]-methionine enkephalinamide H-Tyr-D-Ala-Gly-Phe-Met-NH2 Enkephalin, Amide-[D-Ala2, Met5]

Description	[D-Ala2]-Met-Enkephalinamide, an opioid peptide, is a potent opioid agonist. [D-Ala2]-Met-Enkephalinamide decreases bile flow by a central mechanism. [D-Ala2]-Met-Enkephalinamide has analgesic properties[1][2].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Opioid Receptor Signaling Pathways >> Neuronal Signaling >> Opioid Receptor Research Areas >> Neurological Disease
In Vivo	[D-Ala2]-Met-Enkephalinamide decreases bile flow by a central mechanism in Sprague-Dawley rats[1]. Animal Model: Male Sprague-Dawley rats (250-320 g)[1] Dosage: 10, 50, 100, 150, and 200 mg/kg Administration: Intracerebroventrical injection Result: Decreased in bile flow that ranged from 12% to 41%. Decreased bicarbonate secretion into bile.