1346600-71-2

1346600-71-2 structure

Name: Azathioprine-13C4
Chemical Name: 6-(3-methyl-5-nitroimidazol-4-yl)sulfanyl-7H-purine
CAS Number: 1346600-71-2
Molecular Formula: C₉H₇N₇O₂S
Molecular Weight: 281.23300
Catalog: Research Areas Others
Create Date: 2016-07-29 18:04:58
Modify Date: 2024-03-02 14:11:43
Azathioprine-13C4 (BW 57-322-13C4) is the 13C labeled Azathioprine (HY-B0256). Azathioprine (BW 57-322) is an orally active immunosuppressive agent. Azathioprine can be converted in vivo to the active metabolite 6-mercaptopurine (6-MP). Azathioprine has myelosuppressive effects and induces apoptosis[1][2][3].

Name	6-(3-methyl-5-nitroimidazol-4-yl)sulfanyl-7H-purine
Synonyms	Azathioprine-13C4 Azanin-13C4 Imurel-13C4 Imurek-13C4 BW-57-322-13C4 Imuran-13C4 Zytrim-13C4 6-[(1-Methyl-4-nitro-1H-imidazol-5-yl)thio]-1H-purine-13C4

Description	Azathioprine-13C4 (BW 57-322-13C4) is the 13C labeled Azathioprine (HY-B0256). Azathioprine (BW 57-322) is an orally active immunosuppressive agent. Azathioprine can be converted in vivo to the active metabolite 6-mercaptopurine (6-MP). Azathioprine has myelosuppressive effects and induces apoptosis[1][2][3].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Patel, A.A., R.A. Swerlick, and C.O. McCall, Azathioprine in dermatology: the past, the present, and the future. J Am Acad Dermatol, 2006. 55(3): p. 369-89. [2]. Maltzman, J.S. and G.A. Koretzky, Azathioprine: old drug, new actions. J Clin Invest, 2003. 111(8): p. 1122-4. [3]. Dubinsky, M.C., Azathioprine, 6-mercaptopurine in inflammatory bowel disease: pharmacology, efficacy, and safety. Clin Gastroenterol Hepatol, 2004. 2(9): p. 731-43.