Azathioprine-13C4

Modify Date: 2024-03-02 14:11:43

Azathioprine-13C4 Structure
Azathioprine-13C4 structure
Common Name Azathioprine-13C4
CAS Number 1346600-71-2 Molecular Weight 281.23300
Density N/A Boiling Point N/A
Molecular Formula C9H7N7O2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azathioprine-13C4


Azathioprine-13C4 (BW 57-322-13C4) is the 13C labeled Azathioprine (HY-B0256). Azathioprine (BW 57-322) is an orally active immunosuppressive agent. Azathioprine can be converted in vivo to the active metabolite 6-mercaptopurine (6-MP). Azathioprine has myelosuppressive effects and induces apoptosis[1][2][3].

 Names

Name 6-(3-methyl-5-nitroimidazol-4-yl)sulfanyl-7H-purine
Synonym More Synonyms

 Azathioprine-13C4 Biological Activity

Description Azathioprine-13C4 (BW 57-322-13C4) is the 13C labeled Azathioprine (HY-B0256). Azathioprine (BW 57-322) is an orally active immunosuppressive agent. Azathioprine can be converted in vivo to the active metabolite 6-mercaptopurine (6-MP). Azathioprine has myelosuppressive effects and induces apoptosis[1][2][3].
Related Catalog
References

[1]. Patel, A.A., R.A. Swerlick, and C.O. McCall, Azathioprine in dermatology: the past, the present, and the future. J Am Acad Dermatol, 2006. 55(3): p. 369-89.  

[2]. Maltzman, J.S. and G.A. Koretzky, Azathioprine: old drug, new actions. J Clin Invest, 2003. 111(8): p. 1122-4.  

[3]. Dubinsky, M.C., Azathioprine, 6-mercaptopurine in inflammatory bowel disease: pharmacology, efficacy, and safety. Clin Gastroenterol Hepatol, 2004. 2(9): p. 731-43.  

 Chemical & Physical Properties

Molecular Formula C9H7N7O2S
Molecular Weight 281.23300
Exact Mass 281.05200
PSA 143.40000
LogP 1.66900

 Synonyms

Azathioprine-13C4
Azanin-13C4
Imurel-13C4
Imurek-13C4
BW-57-322-13C4
Imuran-13C4
Zytrim-13C4
6-[(1-Methyl-4-nitro-1H-imidazol-5-yl)thio]-1H-purine-13C4