142638-79-7

142638-79-7 structure

Name: L-703014
Chemical Name: (3R)-5-(1H-indol-3-yl)-3-[[2-(4-piperidin-4-ylbutanoylamino)acetyl]amino]pentanoic acid
CAS Number: 142638-79-7
Molecular Formula: C₂₄H₃₄N₄O₄
Molecular Weight: 442.55100
Catalog: Research Areas Others
Create Date: 2016-05-06 13:26:37
Modify Date: 2024-09-11 07:12:26
L-703014 is a fibrinogen receptor antagonist, with the IC50 of 94 nM, that acts as a novel parenteral and potential oral antithrombotic agent[1][2].

Name	(3R)-5-(1H-indol-3-yl)-3-[[2-(4-piperidin-4-ylbutanoylamino)acetyl]amino]pentanoic acid
Synonyms	l 703,014

Description	L-703014 is a fibrinogen receptor antagonist, with the IC50 of 94 nM, that acts as a novel parenteral and potential oral antithrombotic agent[1][2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. J S Barrett, et al. Pharmacokinetics and Pharmacodynamics of L-703,014, a Potent Fibrinogen Receptor Antagonist, After Intravenous and Oral Administration in the Dog. Pharm Res. 1994 Mar;11(3):426-31. [2]. R M Scarborough, et al. Platelet glycoprotein IIb-IIIa antagonists as prototypical integrin blockers: novel parenteral and potential oral antithrombotic agents. J Med Chem. 2000 Sep 21;43(19):3453-73.