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598-78-7

598-78-7 structure
598-78-7 structure

Name 2-Chloropropionic acid
Synonyms QVYG1
2-Chloropropionicacid
2-Chloropropanoic acid
2-chloro-propionicaci
EINECS 209-952-3
2-Chloropropionic ac
Propionic acid, α-chloro-
RARECHEM AL BO 1240
2-chloropropionic
2-chloro-propanoicaci
Propanoic acid, 2-chloro-
MFCD00004224
α-Monochloropropanoic acid
2-Chlorpropionsure
Density 1.3±0.1 g/cm3
Boiling Point 189.0±13.0 °C at 760 mmHg
Melting Point -12--14 °C
Molecular Formula C3H5ClO2
Molecular Weight 108.524
Flash Point 101.7±0.0 °C
Exact Mass 107.997810
PSA 37.30000
LogP 0.30
Vapour Pressure 0.3±0.7 mmHg at 25°C
Index of Refraction 1.441
Stability Stable. Incompatible with strong oxidizing agents, strong bases.
Water Solubility freely soluble

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UE8575000
CHEMICAL NAME :
Propionic acid, 2-chloro-
CAS REGISTRY NUMBER :
598-78-7
BEILSTEIN REFERENCE NO. :
1720259
LAST UPDATED :
199712
DATA ITEMS CITED :
11
MOLECULAR FORMULA :
C3-H5-Cl-O2
MOLECULAR WEIGHT :
108.53
WISWESSER LINE NOTATION :
QVYG1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
800 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Kidney, Ureter, Bladder - hematuria Skin and Appendages - hair
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0555355
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
400 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Kidney, Ureter, Bladder - hematuria Skin and Appendages - hair
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0555355
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
126 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85INA8 "Documentation of the Threshold Limit Values and Biological Exposure Indices," 5th ed., Cincinnati, OH, American Conference of Governmental Industrial Hygienists, Inc., 1986 Volume(issue)/page/year: 5,136(89),1986 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
7182 mg/kg/42D-C
TOXIC EFFECTS :
Gastrointestinal - changes in structure or function of esophagus Skin and Appendages - hair Related to Chronic Data - changes in testicular weight
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0555355 *** REVIEWS *** ACGIH TLV-TWA 0.44 mg/m3 (0.1 ppm) (skin) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 2 mg/m3;Skin JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV
Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger
Hazard Statements H302-H314
Precautionary Statements P280-P305 + P351 + P338-P310
Personal Protective Equipment Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes C:Corrosive
Risk Phrases R21/22;R35
Safety Phrases S23-S26-S28-S36-S45-S36/37/39-S28A
RIDADR UN 2511 8/PG 3
WGK Germany 1
RTECS UE8575000
Packaging Group III
Hazard Class 8
HS Code 29159080
HS Code 29159080