106881-07-6

106881-07-6 structure

106881-07-6 structure

Name: BOC-L-phenylalanine-d8
Chemical Name: (2S)-2,3,3-trideuterio-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-(2,3,4,5,6-pentadeuteriophenyl)propanoic acid
CAS Number: 106881-07-6
Molecular Formula: C₁₄H₁₁D₈NO₄
Molecular Weight: 273.35
Create Date: 2018-11-27 01:26:30
Modify Date: 2024-01-09 18:14:55
BOC-L-phenylalanine-d8 is the deuterium labeled BOC-L-phenylalanine[1].

Name	(2S)-2,3,3-trideuterio-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-(2,3,4,5,6-pentadeuteriophenyl)propanoic acid
Synonyms	Boc-Phe-OH-phenyl-d5-2,3,3-d3 L-Phenyl-d5-alanine-2,3,3-d3,N-t-Boc derivative MFCD01075441

Description	BOC-L-phenylalanine-d8 is the deuterium labeled BOC-L-phenylalanine[1].
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Melting Point	85-87ºC(lit.)
Molecular Formula	C₁₄H₁₁D₈NO₄
Molecular Weight	273.35
Exact Mass	273.18200
PSA	75.63000
LogP	2.59790

RIDADR	NONH for all modes of transport
WGK Germany	3