88181-11-7

88181-11-7 structure

88181-11-7 structure

Name: Boc-L-Ala-OH-d
Chemical Name: l-alanine-2-d1-n-t-boc
CAS Number: 88181-11-7
Molecular Formula: C₈H₁₄DNO₄
Molecular Weight: 190.22
Create Date: 2018-03-13 08:00:00
Modify Date: 2024-01-14 17:39:19
Boc-L-Ala-OH-d is the deuterium labeled Boc-L-Ala-OH[1].

Name	l-alanine-2-d1-n-t-boc
Synonyms	tert-butyloxycarbonyl-D-valine t-Boc-L-alanine-2-d1 tBoc-DVal-OH (R)-Boc-Val-OH Boc-L-Val-OH N-t-butyloxycarbonyl-D-valine Boc-L-<2-(2)H>alanine N-(tert-Butoxycarbonyl)-D-valine N-(tert-butoxycarbonyl)-L-alanine-d1 Boc-D-Val-OH Boc-D-valine

Description	Boc-L-Ala-OH-d is the deuterium labeled Boc-L-Ala-OH[1].
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Density	1.133 g/cm3
Boiling Point	320.912ºC at 760 mmHg
Molecular Formula	C₈H₁₄DNO₄
Molecular Weight	190.22
Flash Point	147.883ºC
Exact Mass	190.10600
PSA	75.63000
LogP	1.37510

24424-99-5 structure

24424-99-5

21386-65-2 structure

21386-65-2

~63%

88181-11-7 structure

88181-11-7

Literature: Oboodi, M. Reza; Alva, Carlos; Diem, Max Journal of Physical Chemistry, 1984 , vol. 88, # 3 p. 501 - 505

Precursor 2
24424-99-5 21386-65-2
DownStream 0