230960-31-3

230960-31-3 structure

Name: Neuropeptide SF(mouse,rat)
Chemical Name: L-Seryl-L-leucyl-L-alanyl-L-alanyl-L-prolyl-L-glutaminyl-L-arginy l-L-phenylalaninamide
CAS Number: 230960-31-3
Molecular Formula: C₄₀H₆₅N₁₃O₁₀
Molecular Weight: 888.02500
Catalog: Signaling Pathways GPCR/G Protein Neuropeptide Y Receptor
Create Date: 2017-12-19 12:55:36
Modify Date: 2024-01-08 16:25:09
Neuropeptide SF (mouse,rat) is a potent neuropeptide FF receptor agonist with Ki values are 48.4 nM and 12.1 nM for NPFF1 and NPFF2, respectively. Neuropeptide SF increases the amplitude of the sustained current of heterologously expressed acid sensing ion channel 3 (ASIC3) [1].

Name	L-Seryl-L-leucyl-L-alanyl-L-alanyl-L-prolyl-L-glutaminyl-L-arginy l-L-phenylalaninamide

Description	Neuropeptide SF (mouse,rat) is a potent neuropeptide FF receptor agonist with Ki values are 48.4 nM and 12.1 nM for NPFF1 and NPFF2, respectively. Neuropeptide SF increases the amplitude of the sustained current of heterologously expressed acid sensing ion channel 3 (ASIC3) [1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> Neuropeptide Y Receptor
Target	Ki: 48.4 nM (NPFF1) Ki: 12.1 nM (NPFF2)[1]
References	[1]. Miklós Jászberényi, et al. The actions of neuropeptide SF on the hypothalamic-pituitary-adrenal axis and behavior in rats.Regul Pept. 2014 Jan 10;188:46-51. [2]. C Gouardères, et al. Quantitative autoradiographic distribution of NPFF1 neuropeptide FF receptor in the rat brain and comparison with NPFF2 receptor by using [125I]YVP and [(125I]EYF as selective radioligands. Neuroscience. 2002;115(2):349-61.