Neuropeptide SF(mouse,rat)

Modify Date: 2024-01-08 16:25:09

Neuropeptide SF(mouse,rat) Structure
Neuropeptide SF(mouse,rat) structure
Common Name Neuropeptide SF(mouse,rat)
CAS Number 230960-31-3 Molecular Weight 888.02500
Density N/A Boiling Point N/A
Molecular Formula C40H65N13O10 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Neuropeptide SF(mouse,rat)


Neuropeptide SF (mouse,rat) is a potent neuropeptide FF receptor agonist with Ki values are 48.4 nM and 12.1 nM for NPFF1 and NPFF2, respectively. Neuropeptide SF increases the amplitude of the sustained current of heterologously expressed acid sensing ion channel 3 (ASIC3) [1].

 Names

Name L-Seryl-L-leucyl-L-alanyl-L-alanyl-L-prolyl-L-glutaminyl-L-arginy l-L-phenylalaninamide

 Neuropeptide SF(mouse,rat) Biological Activity

Description Neuropeptide SF (mouse,rat) is a potent neuropeptide FF receptor agonist with Ki values are 48.4 nM and 12.1 nM for NPFF1 and NPFF2, respectively. Neuropeptide SF increases the amplitude of the sustained current of heterologously expressed acid sensing ion channel 3 (ASIC3) [1].
Related Catalog
Target

Ki: 48.4 nM (NPFF1) Ki: 12.1 nM (NPFF2)[1]

References

[1]. Miklós Jászberényi, et al. The actions of neuropeptide SF on the hypothalamic-pituitary-adrenal axis and behavior in rats.Regul Pept. 2014 Jan 10;188:46-51.

[2]. C Gouardères, et al. Quantitative autoradiographic distribution of NPFF1 neuropeptide FF receptor in the rat brain and comparison with NPFF2 receptor by using [125I]YVP and [(125I]EYF as selective radioligands. Neuroscience. 2002;115(2):349-61.

 Chemical & Physical Properties

Molecular Formula C40H65N13O10
Molecular Weight 888.02500
Exact Mass 887.49800
PSA 412.16000
LogP 4.71880