634924-89-3

634924-89-3 structure

Name: ANR 94
Chemical Name: 8-ethoxy-9-ethylpurin-6-amine
CAS Number: 634924-89-3
Molecular Formula: C₉H₁₃N₅O
Molecular Weight: 207.23200
Catalog: Signaling Pathways GPCR/G Protein Adenosine Receptor
Create Date: 2016-01-06 21:47:19
Modify Date: 2024-01-06 12:51:38
ANR94 is a potent and selective adenosine A2A receptor (AA2AR) antagonist with an Ki of 46 nM for hAA2AR. ANR94 has the potential for the research of Parkinson's disease[1][2].

Name	8-ethoxy-9-ethylpurin-6-amine
Synonyms	9H-Purin-6-amine,8-ethoxy-9-ethyl

Description	ANR94 is a potent and selective adenosine A2A receptor (AA2AR) antagonist with an Ki of 46 nM for hAA2AR. ANR94 has the potential for the research of Parkinson's disease[1][2].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> Adenosine Receptor
Target	A2AR:46 nM (Ki, human)
References	[1]. Volpini R, et al. Adenosine A2A receptor antagonists: new 8-substituted 9-ethyladenines as tools for in vivo rat models of Parkinson's disease. ChemMedChem. 2009;4(6):1010-1019. [2]. Micioni Di Bonaventura MV, et al. Regulation of adenosine A2A receptor gene expression in a model of binge eating in the amygdaloid complex of female rats. J Psychopharmacol. 2019;33(12):1550-1561.