4563-84-2

4563-84-2 structure

Name: Sulfamethoxazole sodium
Chemical Name: sodium N-(5-methylisoxazol-3-yl)sulphanilamidate
CAS Number: 4563-84-2
Molecular Formula: C₁₀H₁₀N₃NaO₃S
Molecular Weight: 275.259
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2018-07-20 15:51:55
Modify Date: 2025-08-20 14:36:33
Sulfamethoxazole sodium (Ro 4-2130 sodium) is a sulfonamide bacteriostatic antibiotic[1]. Sulfamethoxazole sodium is used to treat various urinary tract pathogens and in combination with Trimethoprim is considered the gold standard in the treatment of urinary tract infections (UTIs)[2].

Name	sodium N-(5-methylisoxazol-3-yl)sulphanilamidate
Synonyms	Sulfisomezole sodium Sodium sulfamethoxazole Sulfamethoxazolesodium Sulfamethoxazole sodium salt Sodium [(4-aminophenyl)sulfonyl](5-methyl-1,2-oxazol-3-yl)azanide 4-Amino-N-(5-methyl-3-isoxazolyl)benzenesulfonamide monosodium salt SMZ-Na Benzenesulfonamide, 4-amino-N-(5-methyl-3-isoxazolyl)-, sodium salt (1:1)

Description	Sulfamethoxazole sodium (Ro 4-2130 sodium) is a sulfonamide bacteriostatic antibiotic[1]. Sulfamethoxazole sodium is used to treat various urinary tract pathogens and in combination with Trimethoprim is considered the gold standard in the treatment of urinary tract infections (UTIs)[2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Straub JO, et al. Aquatic environmental risk assessment for human use of the old antibiotic sulfamethoxazole in Europe. Environ Toxicol Chem. 2016 Apr;35(4):767-79. [2]. Choonara BF, et al. A menthol-based solid dispersion technique for enhanced solubility and dissolution of sulfamethoxazole from an oral tablet matrix. AAPS PharmSciTech. 2015 Aug;16(4):771-86.