102130-43-8

102130-43-8 structure

Name: Atractyloside potassium salt
Chemical Name: atractyloside potassium salt
CAS Number: 102130-43-8
Molecular Formula: C₃₀H₄₄K₂O₁₆S₂
Molecular Weight: 802.987
Catalog: Research Areas Others
Create Date: 2018-06-06 20:23:09
Modify Date: 2024-01-02 17:35:04
Atractyloside potassium salt is a toxic diterpenoid glycoside isolated from the fruits of Xanthium sibiricum. Atractyloside potassium salt is a powerful and specific inhibitor of mitochondrial ADP/ATP transport. Atractyloside potassium salt inhibits chloride channels from mitochondrial membranes of rat heart[1][2][3].

Name	atractyloside potassium salt
Synonyms	ATRACTYLOSIDE,DIPOTASSIUM SALT,ATRACTYLIS GUMMIFERA Atractyloside Dipotassium Salt ATR,2K Dipotassium (1R,4R,5R,7R,9R,10S,13R,15S)-5-carboxy-15-hydroxy-9-methyl-14-methylenetetracyclo[11.2.1.0.0]hexadec-7-yl 2-O-(3-methylbutanoyl)-3,4-di-O-sulfonato-α-D-glucopyranoside MFCD00078810

Description	Atractyloside potassium salt is a toxic diterpenoid glycoside isolated from the fruits of Xanthium sibiricum. Atractyloside potassium salt is a powerful and specific inhibitor of mitochondrial ADP/ATP transport. Atractyloside potassium salt inhibits chloride channels from mitochondrial membranes of rat heart[1][2][3].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Nikles S, et al. Influence of Processing on the Content of Toxic Carboxyatractyloside and Atractyloside and the Microbiological Status of Xanthium sibiricum Fruits (Cang'erzi). Planta Med. 2015 Aug;81(12-13):1213-20. [2]. Lemasters JJ, et al. Phosphate dependence and atractyloside inhibition of mitochondrial oxidative phosphorylation. The ADP-ATP carrier is rate-limiting. J Biol Chem. 1979 Feb 25;254(4):1248-51. [3]. Malekova L, et al. Bongkrekic acid and atractyloside inhibits chloride channels from mitochondrial membranes of rat heart. Biochim Biophys Acta. 2007 Jan;1767(1):31-44.