77-22-5

77-22-5 structure

Name: caramiphen
Chemical Name: 2-(diethylamino)ethyl 1-phenylcyclopentane-1-carboxylate
CAS Number: 77-22-5
Molecular Formula: C₁₈H₂₇NO₂
Molecular Weight: 289.41200
Catalog: Inorganic chemical industry Inorganic salt Metal halides and halides Metal bromide and salt
Create Date: 2018-06-07 10:30:31
Modify Date: 2026-08-06 21:46:10

Name	2-(diethylamino)ethyl 1-phenylcyclopentane-1-carboxylate
Synonyms	CYCLOPENTANECARBOXYLIC ACID,1-PHENYL-,2-(DIETHYLAMINO)ETHYL ESTER Pentaphen (pharmaceutical) EINECS 201-013-6 1-phenyl-cyclopentanecarboxylic acid-(2-diethylamino-ethyl ester) Caramiphen Pentoxyverine impurity B CRS 2-(Diethylamino)ethyl 1-phenylcyclopentanecarboxylate camiphen Caramiphenum [INN-Latin] 1-Phenyl-1-cyclopentanecboxylic acid 2-(diethylamino)ethyl camiphen //BP Pentoxyverine Impurity B 1-Phenyl-cyclopentancarbonsaeure-(2-diaethylamino-aethylester) Caramiphene [INN-French] Pentaphen Caramifenio [INN-Spanish] Parpanil amiphen 1-Phenyl-cyclopentan-1-carbonsaeure-<2-diethylamino-ethylester> Pentoxyverine hydrogen citrate Impurity B 2-(Diethylamino)ethyl 1-phenylcyclopentanecboxylate 1-(2-Diethylaminoethoxycbonyl)-1-phenylcyclopentane 1-Phenyl-cyclopentan-carbonsaeure-(1)-<2-diethylamino-ethylester> 1-phenylcyclopentanecboxylic acid 2-diethylaminoethyl ester 2-diethylaminoethyl 1-phenylcyclopentane-1-cboxylate Cyclopentanecboxylic acid, 1-phenyl-, 2-(diethylamino)ethyl ester 1-Phenyl-1-cyclopentanecboxylic acid 2-(diethylamino)ethyl ester

Density	1.038g/cm3
Boiling Point	392.1ºC at 760 mmHg
Molecular Formula	C₁₈H₂₇NO₂
Molecular Weight	289.41200
Flash Point	124.8ºC
Exact Mass	289.20400
PSA	29.54000
LogP	3.38340
Index of Refraction	1.523

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GY3700000

CHEMICAL NAME :: Cyclopentanecarboxylic acid, 1-phenyl-, 2-(diethylamino)ethyl ester

CAS REGISTRY NUMBER :: 77-22-5

BEILSTEIN REFERENCE NO. :: 2144901

LAST UPDATED :: 199706

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C18-H27-N-O2

MOLECULAR WEIGHT :: 289.46

WISWESSER LINE NOTATION :: L5TJ AVO2N2&2 AR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 80 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: APPNAH Acta Physiologica et Pharmacologica Neerlandica. (Amsterdam, Netherlands) V.1-15, 1950-69. For publisher information, see EJPHAZ. Volume(issue)/page/year: 1,4,1950

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 180 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 111,293,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 365 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: HPPAAL Helvetica Physiologia et Pharmacologica Acta. (Basel, Switzerland) V.1-26, 1943-68. Discontinued. Volume(issue)/page/year: 16,277,1958

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 570 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: HPPAAL Helvetica Physiologia et Pharmacologica Acta. (Basel, Switzerland) V.1-26, 1943-68. Discontinued. Volume(issue)/page/year: 16,277,1958

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 67 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold

REFERENCE :: SMWOAS Schweizerische Medizinische Wochenschrift. (Schwabe & Co., Steintorst 13, 4010 Basel, Switzerland) V.50- 1920- Volume(issue)/page/year: 76,1282,1946

100-37-8

77-22-5

Literature: Tilford; Van Campen; Shelton Journal of the American Chemical Society, 1947 , vol. 69, p. 2902,2904

17380-62-0

100-37-8

77-22-5

Literature: Geigy A.G. Patent: US2404588 , 1944 ; Full Text Show Details Geigy A.G. Patent: CH234452 , 1942 ;

77-55-4

77-22-5

Literature: Mndshojan et al. Doklady Akademii Nauk Armyanskoi SSR, 1958 , vol. 27, p. 93,96, 97 Chem.Abstr., 1959 , p. 18904

77-57-6

77-22-5

Literature: Mndshojan et al. Doklady Akademii Nauk Armyanskoi SSR, 1958 , vol. 27, p. 93,96, 97 Chem.Abstr., 1959 , p. 18904

140-29-4

77-22-5

Literature: Mndshojan et al. Doklady Akademii Nauk Armyanskoi SSR, 1958 , vol. 27, p. 93,96, 97 Chem.Abstr., 1959 , p. 18904

77-55-4

100-35-6

77-22-5

Literature: Geigy A.G. Patent: CH240169 , 1942 ;

109-89-7

77-22-5

Literature: Geigy A.G. Patent: CH242289 , 1942 ;

Precursor 7
100-37-8 17380-62-0 77-55-4 77-57-6
140-29-4 100-35-6 109-89-7
DownStream 0

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

941932-28-1	941972-97-0
941993-05-1	941932-40-7
941993-11-9	941993-13-1
941993-15-3	919753-90-5
919846-95-0	919846-99-4